| 52' | RB Leipzig | 1-0 (0-0) | Atletico Madrid |
| 15' | Elche | 0-0 | Saragosse |
| 15' | Cerro Porteno | 0-0 | Club Guarani |
| 00h15 | Sao Paulo | Fortaleza | |||
| 00h30 | Internacional | Santos | |||
| 01h00 | Vasco Da Gama | Sport Recife |
| 02h00 | Atlas | Toluca | |||
| 04h00 | Club America | Santos Laguna |
| 00h30 | Olimpia | Libertad |
| FT | Newcastle Jets FC | 3-0 (1-0) | Wellington Phoenix |
| FT | Atletico Mineiro | 3-2 (0-2) | Corinthians | ||
| FT | Atletico Paranaense | 2-1 (1-1) | Goias | ||
| FT | Bragantino | 1-1 (1-0) | Botafogo | ||
| FT | Atletico Goianiense | 3-0 (2-0) | Flamengo | ||
| FT | Bahia | 1-0 (1-0) | Coritiba | ||
| FT | Ceara | 1-1 (1-0) | Gremio | ||
| FT | Fluminense | 1-1 (1-1) | Palmeiras |
| FT | Girona | 1-0 (0-0) | Almeria |
| Rep. | Atlanta United FC | Reporté | New England Revolution | ||
| Rep. | FC Cincinnati | Reporté | Los Angeles FC | ||
| FT | FC Dallas | 0-1 (0-0) | Nashville SC |
| Rep. | Zhetysu | Reporté | FC Kyzyl-Zhar SK |
| FT | Club Queretaro | 1-0 (1-0) | Cruz Azul | ||
| FT | FC Juarez | 0-2 (0-0) | Guadalajara-Chivas | ||
| FT | U.N.A.M. - Pumas | 1-1 (1-0) | Monterrey | ||
| FT | Club Tijuana | 0-2 (0-1) | Atletico San Luis |
| FT | 12 De Octubre | 1-0 (0-0) | Club Sp. San Lorenzo |
| FT | AIK Stockholm | 0-1 (0-1) | Ostersunds Fk | ||
| FT | If Elfsborg | 4-2 (4-0) | Falkenbergs Ff | ||
| FT | Ifk Norrkoping | 1-2 (0-1) | Hammarby | ||
| FT | Ik Sirius | 3-1 (2-0) | Helsingborg | ||
| FT | Kalmar Ff | 1-1 (1-1) | IFK Göteborg | ||
| FT | Varbergs Bois FC | 1-3 (1-2) | Hacken |
