| FT | Tigres | 7-0 (2-0) | Puebla | ||
| FT | CF America | 1-0 (1-0) | Queretaro FC | ||
| FT | Mazatlan FC | 2-2 (0-1) | Tijuana | ||
| FT | Atlas | 0-3 (0-3) | Pachuca |
| FT | CF Montreal | 1-1 (1-0) | Atlanta United | ||
| FT | New England Revolution | 2-0 (0-0) | DC United | ||
| FT | Philadelphia Union | 1-1 (1-0) | Toronto FC | ||
| FT | Austin FC | 2-2 (2-0) | Houston Dynamo FC | ||
| FT | Chicago Fire FC | 2-2 (1-1) | Los Angeles FC | ||
| FT | FC Dallas | 2-0 (1-0) | Portland Timbers | ||
| FT | St. Louis City | 3-1 (2-0) | Nashville SC | ||
| FT | Sporting Kansas City | 0-2 (0-1) | San Diego FC | ||
| FT | San Jose Earthquakes | 2-1 (0-0) | Vancouver Whitecaps |
| FT | Millonarios | 3-3 (2-1) | Deportivo Cali | ||
| FT | Once Caldas | 1-1 (1-1) | Aguilas Doradas | ||
| FT | America de Cali | 0-1 (0-1) | Tolima | ||
| FT | Bucaramanga | 2-1 (1-1) | Santa Fe |
| FT | Flamengo | 2-1 (1-0) | Mirassol | ||
| FT | Red Bull Bragantino | 1-3 (0-2) | Internacional | ||
| FT | Sao Paulo | 2-0 (1-0) | Vitoria | ||
| FT | Fortaleza | 0-5 (0-2) | Botafogo RJ | ||
| FT | Bahia | 3-3 (2-1) | Fluminense |
| FT | Orense | 1-1 (1-0) | Universidad Catolica | ||
| FT | Mushuc Runa | 1-2 (1-1) | Libertad | ||
| FT | Aucas | 1-0 (1-0) | LDU de Quito | ||
| FT | Manta | 0-0 (0-0) | Independiente del Valle |
| FT | Newell's Old Boys | 1-1 (0-0) | Central Cordoba de Santiago | ||
| FT | Lanus | 1-0 (1-0) | Talleres | ||
| FT | San Martin San Juan | 0-1 (0-0) | Sarmiento | ||
| FT | Boca Juniors | 1-1 (0-0) | Racing Club | ||
| FT | Independiente | 0-0 (0-0) | River Plate | ||
| FT | Atletico Tucuman | 0-0 (0-0) | Rosario Central | ||
| FT | Belgrano | 2-1 (1-0) | Banfield |
| FT | General Caballero JLM | 3-2 (0-2) | Sportivo Ameliano | ||
| FT | Luqueno | 5-1 (1-0) | Atletico Tembetary |
| FT | Huachipato | 1-0 (0-0) | Union La Calera | ||
| FT | Universidad de Chile | 4-1 (1-1) | Union Espanola | ||
| FT | La Serena | 3-3 (1-0) | O'Higgins |
| FT | Nacional | 0-2 (0-2) | Gil Vicente | ||
| FT | Arouca | 3-1 (1-0) | AVS Futebol SAD |
| FT | Leganes | 0-0 (0-0) | Real Oviedo | ||
| FT | Racing Santander | 0-0 (0-0) | Cagliari | ||
| FT | Werder Bremen | 0-1 (0-1) | Udinese | ||
| FT | AFC Bournemouth | 1-1 (1-0) | Real Sociedad | ||
| FT | Brighton & Hove Albion | 2-0 (1-0) | VFL Wolfsburg | ||
| Pen. | *Manchester United | 1-1(1-1) | Fiorentina | ||
| FT | Augsburg | 0-1 (0-1) | Sunderland | ||
| FT | FC Heidenheim | 2-1 (2-0) | Parma Calcio 1913 | ||
| FT | FC Koeln | 4-0 (2-0) | Atalanta | ||
| FT | Freiburg | 2-2 (1-0) | Osasuna | ||
| FT | Mainz 05 | 0-0 (0-0) | Strasbourg | ||
| FT | Union Berlin | 0-1 (0-0) | Olympiacos | ||
| FT | Werder Bremen | 1-2 (0-2) | Udinese | ||
| FT | Burnley | 0-1 (0-0) | Lazio | ||
| FT | Everton | 0-1 (0-0) | Roma | ||
| FT | Leeds United | 1-1 (0-1) | AC Milan | ||
| FT | St. Pauli | 1-0 (1-0) | Hellas Verona | ||
| Pen. | *West Ham United | 1-1(1-1) | Lille | ||
| FT | Wolverhampton Wanderers | 0-1 (0-0) | Celta Vigo | ||
| FT | Hoffenheim | 8-0 (5-0) | Metz | ||
| FT | Angers | 1-0 (0-0) | Lorient | ||
| FT | Newcastle United | 0-2 (0-0) | Atletico Madrid | ||
| FT | VfB Stuttgart | 0-1 (0-1) | Bologna | ||
| Pen. | *Arsenal | 3-0(3-0) | Athletic Bilbao | ||
| FT | Brest | 1-1 (1-1) | Sassuolo | ||
| FT | Brighton & Hove Albion | 2-1 (1-0) | VFL Wolfsburg | ||
| FT | Fulham | 1-0 (1-0) | Eintracht Frankfurt | ||
| FT | Lens | 2-1 (0-0) | RB Leipzig | ||
| FT | Reggiana | 0-0 (0-0) | Cremonese | ||
| FT | Rennes | 2-2 (1-0) | Genoa | ||
| FT | AFC Bournemouth | 0-0 (0-0) | Real Sociedad | ||
| FT | Auxerre | 0-2 (0-0) | Levante | ||
| FT | Eibar | 0-0 (0-0) | Deportivo Alaves | ||
| FT | Lyon | 2-1 (1-1) | Getafe | ||
| FT | Marseille | 3-1 (1-1) | Aston Villa | ||
| FT | Nantes | 2-3 (2-1) | Paris FC | ||
| FT | Naples | 3-2 (3-2) | Girona | ||
| FT | Racing Santander | 1-1 (0-0) | Cagliari | ||
| FT | Deportivo La Coruna | 2-0 (0-0) | Le Havre | ||
| FT | Mallorca | 2-0 (1-0) | Hamburger SV | ||
| FT | Elche | 1-0 (0-0) | Hercules | ||
| FT | Monopoli | 2-2 (0-2) | Lecce | ||
| FT | Real Betis | 1-3 (0-1) | Malaga | ||
| FT | Nottingham | 0-0 (0-0) | Al Qadasiya | ||
| FT | Palermo | 0-3 (0-1) | Manchester City | ||
| FT | Valencia | 3-0 (2-0) | Torino |
| FT | Sloga Doboj | 2-1 (2-0) | FK Sarajevo | ||
| FT | Zeljeznicar | 1-1 (0-0) | Rudar Prijedor |
| FT | NEC Nijmegen | 5-0 (1-0) | Excelsior | ||
| FT | Feyenoord | 2-0 (1-0) | NAC Breda | ||
| FT | SC Heerenveen | 1-1 (1-0) | FC Volendam | ||
| FT | PSV Eindhoven | 6-1 (3-0) | Sparta Rotterdam |
| FT | NK Istra 1961 | 2-2 (0-1) | NK Lokomotiva | ||
| FT | Osijek | 0-0 (0-0) | Rijeka |
| FT | FK Radnik Surdulica | 3-1 (2-0) | Cukaricki | ||
| FT | FK Crvena Zvezda | 1-0 (1-0) | TSC Backa Topola | ||
| FT | FK Spartak Subotica | 1-1 (1-0) | Mladost Lucani | ||
| FT | OFK Beograd | 1-2 (1-1) | Vojvodina |
| FT | Club Brugge | 2-0 (0-0) | Cercle Bruges | ||
| FT | Westerlo | 0-1 (0-0) | KV Mechelen | ||
| FT | La Gantoise | 2-3 (0-1) | Union St.Gilloise |
| FT | Samsunspor | 2-1 (1-0) | Genclerbirligi | ||
| FT | Antalyaspor | 2-1 (2-1) | Kasimpasa |
| FT | Dynamo Dresden | 1-2 (1-2) | Magdeburg | ||
| FT | Eintracht Braunschweig | 3-2 (2-1) | Greuther Fuerth | ||
| FT | Fortuna Duesseldorf | 0-2 (0-0) | Hannover 96 | ||
| FT | Kaiserslautern | 1-0 (0-0) | Schalke 04 |
| FT | UTA Arad | 2-1 (1-0) | FCV Farul Constanta | ||
| FT | Universitatea Cluj | 1-1 (1-0) | Petrolul Ploiesti |
| FT | Virtus Entella | 4-0 (1-0) | Ternana |
| FT | Skalica | 2-2 (0-1) | Zeleziarne Podbrezova | ||
| FT | Zemplin Michalovce | 2-4 (0-3) | Zilina | ||
| FT | DAC 1904 Dunajska Streda | 2-0 (1-0) | Ruzomberok |
| FT | Saint-Gall | 5-0 (3-0) | Winterthur | ||
| FT | FC Lucerne | 1-2 (1-1) | Thun |
| FT | Longford Town | 2-0 (1-0) | Treaty United |
| FT | NK Bravo | 1-2 (1-0) | Aluminij | ||
| FT | Koper | 1-2 (0-2) | Radomlje |
| FT | MTK Budapest | 5-0 (4-0) | Diosgyori VTK | ||
| FT | Nyiregyhaza Spartacus FC | 1-4 (0-3) | Ferencvarosi TC |
| FT | PFK CSKA Sofia | 0-0 (0-0) | Cherno More Varna | ||
| FT | Slavia Sofia | 0-3 (0-1) | Ludogorets Razgrad |
| FT | Arka Gdynia | 2-1 (1-1) | Pogon Szczecin | ||
| FT | Widzew Lodz | 1-1 (1-1) | Wisla Plock |
| FT | Anderlecht Futures | 1-3 (1-1) | Kortrijk | ||
| FT | Eupen | 2-0 (0-0) | FC Liege | ||
| FT | K. Lierse SK | 0-2 (0-1) | SK Beveren | ||
| FT | Patro Eisden | 2-1 (1-0) | KSC Lokeren | ||
| FT | RWDM Brussels | 3-3 (1-0) | Lommel |
| FT | Guingamp | 3-3 (0-2) | Le Mans | ||
| FT | Dunkerque | 2-2 (1-2) | Clermont Foot | ||
| FT | Laval | 3-3 (2-2) | St-Etienne | ||
| FT | Montpellier | 1-1 (1-1) | Red Star | ||
| FT | Pau | 2-0 (1-0) | Annecy FC | ||
| FT | Rodez | 0-0 (0-0) | Nancy | ||
| FT | Troyes | 2-1 (1-1) | Grenoble |
| FT | FC Zlin | 3-2 (2-1) | Mlada Boleslav | ||
| FT | Slovan Liberec | 2-0 (1-0) | Dukla Praha | ||
| FT | Viktoria Plzen | 1-1 (1-0) | Slovacko | ||
| FT | Slavia Prague | 3-0 (1-0) | Teplice |
| FT | FC Smorgon | 0-0 (0-0) | FK Slutsk | ||
| FT | Isloch | 2-0 (0-0) | BATE Borisov | ||
| FT | FK Vitebsk | 1-2 (1-2) | FC Minsk |
| FT | Altach | 1-0 (0-0) | Ried | ||
| FT | BW Linz | 0-1 (0-1) | Hartberg | ||
| FT | Red Bull Salzbourg | 5-0 (1-0) | Grazer AK |
| FT | Krylya Sovetov Samara | 1-1 (1-0) | Baltika | ||
| FT | CSKA Moscow | 5-1 (4-1) | Rubin Kazan | ||
| FT | Lokomotiv Moscow | 4-2 (1-1) | Spartak Moscow | ||
| FT | FK Akhmat | 1-0 (1-0) | Zenit St. Petersburg |
| FT | Molde | 1-0 (1-0) | Hamarkameratene | ||
| FT | Bodoe/Glimt | 1-1 (1-1) | Tromsoe |
| FT | Pacos de Ferreira | 1-2 (1-0) | Vizela | ||
| FT | Torreense | 0-1 (0-0) | Sporting CP B | ||
| FT | Portimonense | 2-1 (1-1) | Penafiel |
| FT | Central African Republic | 0-1 (0-1) | Mauritanie | ||
| FT | Tanzania | 2-1 (2-1) | Madagascar |
| FT | Livingston | 3-1 (2-0) | Falkirk | ||
| FT | St. Mirren | 0-0 (0-0) | Motherwell | ||
| FT | Rangers | 1-1 (0-0) | Dundee FC |
| FT | Charlton Athletic | 1-0 (0-0) | Watford | ||
| FT | Coventry City | 0-0 (0-0) | Hull City | ||
| FT | Southampton | 2-1 (0-1) | Wrexham | ||
| FT | Middlesbrough | 1-0 (0-0) | Swansea City | ||
| FT | Norwich City | 1-2 (0-0) | Millwall | ||
| FT | Oxford United | 0-1 (0-1) | Portsmouth | ||
| FT | Queens Park Rangers | 1-1 (1-0) | Preston North End | ||
| FT | Stoke City | 3-1 (0-0) | Derby County | ||
| FT | West Bromwich Albion | 1-0 (1-0) | Blackburn Rovers | ||
| FT | Sheffield United | 1-4 (1-2) | Bristol City |
| FT | UN Kaerjeng 97 | 2-3 (1-0) | F91 Dudelange | ||
| FT | FC Progres Niederkorn | 1-0 (0-0) | US Mondorf les Bains |
| FT | FF Jaro | 2-1 (0-0) | Haka | ||
| FT | FC KTP | 0-2 (0-1) | KuPS | ||
| FT | IFK Mariehamn | 2-5 (0-2) | IF Gnistan |
| FT | FC Kuressaare | 1-3 (1-3) | Harju Jalgpallikool | ||
| FT | Narva Trans | 4-1 (2-1) | Tammeka | ||
| FT | Paide Linnameeskond | 2-2 (2-1) | Tallinna Kalev |
| FT | FC Telavi | 1-1 (0-1) | Kolkheti-1913 Poti | ||
| FT | Iberia 1999 | 0-0 (0-0) | Torpedo Kutaisi |
| FT | Shelbourne | 2-2 (1-1) | Bohemian FC |
| FT | Malmoe FF | 1-3 (0-0) | Mjaellby | ||
| FT | Halmstads BK | 0-1 (0-0) | Sirius |
| FT | FK Liepaja | 2-1 (0-0) | BFC Daugavpils | ||
| FT | FS Metta/LU | 2-2 (0-1) | FK Jelgava |
| FT | Crusaders | 3-4 (3-2) | Carrick Rangers | ||
| FT | Glenavon | 0-2 (0-1) | Ballymena United | ||
| FT | Portadown | 0-1 (0-1) | Glentoran |
| FT | Cardiff Met University | 2-2 (2-0) | Caernarfon |
| FT | Kryvbas | 2-0 (1-0) | Metalist 1925 | ||
| FT | LNZ Cherkasy | 1-0 (1-0) | Epitsentr Kamianets-Podilskyi |
| FT | Shandong Taishan | 2-1 (1-0) | Changchun Yatai | ||
| FT | Shanghai Shenhua | 1-2 (0-1) | Shanghai Port | ||
| FT | Qingdao Hainiu | 5-1 (2-1) | Yunnan Yukun |
| FT | Dalian Kuncheng | 0-0 (0-0) | Yanbian Longding | ||
| FT | Chongqing Tongliang Long | 0-2 (0-0) | Nantong Zhiyun FC | ||
| FT | Nanjing City FC | 3-3 (3-3) | Shaanxi Union | ||
| FT | Shenzhen Juniors | 2-3 (1-1) | Liaoning Tieren |
| FT | Busan I'Park | 0-2 (0-1) | Incheon United | ||
| FT | Chungnam Asan FC | 2-2 (0-1) | Gyeongnam FC | ||
| FT | Suwon Samsung Bluewings | 3-1 (1-0) | Ansan Greeners | ||
| FT | Seongnam FC | 0-0 (0-0) | Gimpo FC |
| FT | Gangwon FC | 0-0 (0-0) | Gimcheon Sangmu | ||
| FT | Ulsan HD FC | 1-0 (0-0) | Jeju SK |
| FT | Tokyo Verdy | 1-0 (0-0) | Yokohama F.Marinos | ||
| FT | Yokohama FC | 1-2 (0-1) | Urawa Red Diamonds | ||
| FT | Kawasaki Frontale | 2-5 (2-2) | Avispa Fukuoka |
