| FT | Puebla | 2-3 (1-1) | Atlas | ||
| FT | FC Juarez | 1-1 (0-1) | CF America | ||
| FT | Tijuana | 1-0 (1-0) | Queretaro FC | ||
| FT | Santos Laguna | 3-0 (1-0) | Club Universidad Nacional | ||
| FT | Toluca | 3-1 (2-1) | Necaxa | ||
| FT | Cruz Azul | 0-0 (0-0) | Mazatlan FC |
| FT | Orlando City | 1-1 (1-0) | CF Montreal | ||
| FT | Philadelphia Union | 2-0 (2-0) | New York Red Bulls | ||
| FT | Toronto FC | 1-1 (0-0) | Atlanta United | ||
| FT | Inter Miami CF | 2-1 (1-0) | Nashville SC | ||
| FT | Austin FC | 0-0 (0-0) | New England Revolution | ||
| FT | Chicago Fire FC | 1-2 (0-2) | San Diego FC | ||
| FT | Minnesota United | 4-1 (3-0) | San Jose Earthquakes | ||
| FT | Sporting Kansas City | 2-3 (0-3) | Seattle Sounders FC | ||
| FT | FC Cincinnati | 2-4 (2-2) | Columbus Crew | ||
| FT | Charlotte FC | 2-0 (1-0) | New York City FC | ||
| FT | Colorado Rapids | 3-0 (2-0) | Vancouver Whitecaps | ||
| FT | Real Salt Lake | 1-0 (1-0) | Houston Dynamo FC | ||
| FT | LA Galaxy | 2-1 (1-0) | DC United | ||
| FT | Los Angeles FC | 2-0 (2-0) | FC Dallas |
| FT | Once Caldas | 1-3 (0-1) | Atletico Nacional | ||
| FT | Deportivo Pasto | 3-2 (2-0) | Tolima | ||
| FT | Envigado | 0-1 (0-0) | Fortaleza FC | ||
| FT | Bucaramanga | 1-1 (1-1) | Chico FC | ||
| FT | Deportivo Cali | 0-2 (0-1) | Junior FC |
| FT | Castellon | 6-0 (4-0) | Queens Park Rangers | ||
| FT | Lausanne | 4-2 (3-0) | Etoile Carouge | ||
| FT | Nice | 2-1 (1-1) | Cercle Bruges | ||
| FT | PSV Eindhoven | 3-1 (2-1) | Elversberg | ||
| FT | Silkeborg | 3-1 (0-0) | Thisted | ||
| FT | Anderlecht | 2-2 (1-0) | Rakow Czestochowa | ||
| FT | Celtic | 2-3 (1-2) | Estrela da Amadora | ||
| FT | Lens | 2-2 (0-2) | Standard Liege | ||
| FT | Vejle Boldklub | 3-3 (0-0) | Fredericia | ||
| FT | Viborg | 2-0 (0-0) | AaB | ||
| FT | AZ Alkmaar | 3-2 (3-0) | Almere City FC | ||
| FT | Crystal Palace | 1-0 (0-0) | Millwall | ||
| FT | FC Bâle | 1-1 (0-1) | Winterthur | ||
| FT | ADO La Haye | 0-2 (0-2) | Sparta Rotterdam | ||
| FT | Arouca | 0-2 (0-1) | Tondela | ||
| FT | Bergisch Gladbach | 1-7 (1-3) | FC Koeln | ||
| FT | Cove Rangers | 0-2 (0-1) | Aberdeen | ||
| FT | Estoril | 2-1 (0-0) | CF Os Belenenses | ||
| FT | FC Groningen | 2-0 (0-0) | FC Emmen | ||
| FT | Feyenoord | 1-1 (0-1) | Union St.Gilloise | ||
| FT | Matlock Town | 1-1 (0-0) | Derby County | ||
| FT | Moreirense | 1-1 (0-0) | Trofense | ||
| FT | NEC Nijmegen | 1-0 (0-0) | Kaizer Chiefs | ||
| FT | Norwich City | 3-1 (2-1) | Northampton Town | ||
| FT | Randers FC | 0-2 (0-1) | OB | ||
| FT | Rio Ave | 5-0 (3-0) | Leixoes | ||
| FT | Sporting Charleroi | 2-1 (0-0) | FC Liege | ||
| FT | TSV Gersthofen | 0-9 (0-3) | Augsburg | ||
| FT | Vitoria de Guimaraes | 1-0 (1-0) | Pacos de Ferreira | ||
| FT | Heracles | 2-1 (1-1) | FCV Dender EH | ||
| FT | Ried | 4-2 (2-2) | FC Liefering | ||
| FT | Ajax Amsterdam | 1-1 (0-0) | AGF | ||
| FT | Chesterfield | 0-0 (0-0) | Nottingham | ||
| FT | Lausanne | 1-2 (1-0) | Stade Nyonnais | ||
| FT | Lorient | 5-1 (2-1) | FC Fleury 91 | ||
| FT | Panathinaikos | 1-2 (0-1) | Braga | ||
| FT | SV Drochtersen/Assel | 1-0 (0-0) | St. Pauli | ||
| FT | SV Fellbach | 1-7 (0-4) | VfB Stuttgart | ||
| FT | Schalke 04 | 1-0 (1-0) | Saint-Gall | ||
| FT | Brandenburger SC Sued | 1-9 (1-6) | Union Berlin | ||
| FT | Freiberg | 2-3 (1-1) | Hoffenheim | ||
| FT | Parndorf | 0-6 (0-4) | Austria Wien | ||
| FT | Verden 04 | 0-6 (0-3) | Werder Bremen | ||
| FT | Accrington Stanley | 1-2 (0-1) | Blackburn Rovers | ||
| FT | Cray Wanderers | 1-1 (1-1) | Crystal Palace | ||
| FT | Dartford | 2-3 (2-2) | Charlton Athletic | ||
| FT | Eastleigh | 1-2 (1-1) | Southampton | ||
| FT | FC Koebenhavn | 1-0 (1-0) | Hamburger SV | ||
| FT | FK Akhmat | 1-0 (0-0) | Krylya Sovetov Samara | ||
| FT | Leicester City | 2-1 (1-0) | OH Leuven | ||
| FT | Trabzonspor | 1-1 (1-1) | Dinamo Tbilisi | ||
| FT | Watford | 1-1 (0-0) | AFC Wimbledon | ||
| FT | Lokomotiv Moscow | 1-5 (0-0) | Dinamo Moscow | ||
| FT | Rapid Vienne | 5-2 (3-0) | Zilina | ||
| FT | Sturm Graz | 0-0 (0-0) | Polissya Zhytomyr | ||
| FT | Altach | 3-1 (1-1) | FC Lucerne | ||
| FT | FC Dordrecht | 0-5 (0-2) | Anderlecht | ||
| FT | La Gantoise | 1-1 (0-0) | RAAL La Louviere | ||
| FT | Lille | 5-0 (4-0) | Amiens | ||
| FT | NAC Breda | 0-1 (0-1) | Excelsior | ||
| FT | South Shields | 0-4 (0-2) | Sunderland | ||
| FT | Toulouse | 0-0 (0-0) | Pau | ||
| FT | LASK | 7-1 (4-0) | Trencin | ||
| FT | Nantes | 2-0 (0-0) | Laval | ||
| FT | Grazer AK | 1-1 (0-0) | Voitsberg | ||
| FT | Rubin Kazan | 1-0 (1-0) | Ural | ||
| FT | Servette | 1-0 (0-0) | Grenoble | ||
| FT | BW Linz | 3-1 (1-1) | Fortuna Duesseldorf | ||
| FT | Umraniyespor | 2-5 (1-2) | Galatasaray | ||
| FT | FC Séville | 1-3 (0-2) | Birmingham City | ||
| FT | Louisville City FC | 1-2 (1-2) | Leganes |
| FT | Flamengo | 2-0 (0-0) | Sao Paulo | ||
| FT | Internacional | 1-0 (0-0) | Vitoria | ||
| FT | Vasco da Gama | 0-2 (0-0) | Botafogo RJ | ||
| FT | Bahia | 2-1 (0-0) | Atletico MG |
| FT | CSD Macara | 1-2 (1-1) | Independiente del Valle | ||
| FT | Manta | 4-2 (2-1) | Universidad Catolica | ||
| FT | LDU de Quito | 2-0 (1-0) | Emelec | ||
| FT | Barcelona SC | 1-1 (1-1) | Tecnico Universitario |
| FT | Rosario Central | 1-1 (0-0) | Godoy Cruz | ||
| FT | Gimnasia LP | 0-1 (0-1) | Instituto | ||
| FT | Huracan | 0-3 (0-1) | Belgrano | ||
| FT | Racing Club | 0-1 (0-0) | Barracas Central |
| FT | Sportivo Ameliano | 0-1 (0-0) | Cerro Porteno | ||
| FT | Nacional | 1-0 (0-0) | Guarani |
| FT | Universidad de Chile | 2-1 (1-1) | Colo Colo |
| FT | Pologne F | 3-2 (2-0) | Danemark F | ||
| FT | Suède F | 4-1 (3-1) | Allemagne F |
| FT | Sligo Rovers | 2-0 (2-0) | Derry City |
| FT | UTA Arad | 3-3 (0-2) | Universitatea Craiova | ||
| FT | FCSB | 1-1 (0-0) | Hermannstadt |
| FT | Longford Town | 3-1 (2-0) | Kerry FC |
| FT | Stirling Albion | 0-2 (0-0) | Hamilton Academical | ||
| FT | Hearts | 4-1 (1-1) | Dunfermline Athletic |
| FT | Bodoe/Glimt | 2-0 (0-0) | Sandefjord | ||
| FT | Fredrikstad | 4-2 (0-1) | Molde |
| FT | IFK Göteborg | 1-2 (1-2) | Elfsborg | ||
| FT | Malmoe FF | 3-1 (1-0) | IFK Norrkoeping |
| FT | East Kilbride | 1-3 (1-0) | St. Johnstone | ||
| FT | Elgin City | 1-5 (0-3) | Raith Rovers |
| Pen. | Annan Athletic | 1-1(1-1) | Forfar Athletic* | ||
| Pen. | *Arbroath | 0-0(0-0) | St. Mirren |
| Pen. | Clyde | 2-2(2-2) | Motherwell* | ||
| FT | Peterhead | 2-4 (1-2) | Greenock Morton |
| FT | Bonnyrigg Rose | 0-1 (0-1) | Alloa Athletic | ||
| FT | Dundee FC | 0-1 (0-1) | Airdrieonians |
| FT | Brora Rangers | 0-2 (0-1) | Kilmarnock | ||
| FT | East Fife | 1-2 (0-1) | Livingston |
| Pen. | *Stranraer | 1-1(1-1) | Ross County |
| FT | Brechin City | 0-7 (0-4) | Falkirk | ||
| FT | Spartans FC | 2-1 (0-1) | Queen's Park |
| FT | FC Inter Turku | 3-1 (3-0) | FF Jaro |
| FT | Yanbian Longding | 2-0 (0-0) | Guangdong GZ-Power | ||
| FT | Liaoning Tieren | 1-0 (0-0) | Guangxi Pingguo | ||
| FT | Shaanxi Union | 1-3 (0-2) | Suzhou Dongwu | ||
| FT | Foshan Nanshi | 2-1 (2-1) | Shenzhen Juniors | ||
| FT | Qingdao Red Lions | 3-4 (2-2) | Chongqing Tongliang Long |
| FT | Parnu JK Vaprus | 0-0 (0-0) | Narva Trans |
| FT | Busan I'Park | 0-0 (0-0) | Seongnam FC | ||
| FT | Cheonan City | 2-3 (0-1) | Hwaseong FC | ||
| FT | Jeonnam Dragons | 1-0 (1-0) | Gyeongnam FC | ||
| FT | Suwon Samsung Bluewings | 1-0 (0-0) | Cheongju FC |
| FT | Ulsan HD FC | 2-2 (0-1) | Daegu FC |
