| FT | New York City FC | 3-1 (1-0) | Toronto FC |
| Pen. | Club Atletico Platense | 2-2(2-2) | Independiente Rivadavia* | ||
| Pen. | Instituto | 0-0(0-0) | Huracan* |
| FT | Chili F | 5-0 (1-0) | Bolivie F |
| FT | Afturelding | 2-2 (1-2) | Breidablik |
| FT | Belgique F | 0-1 (0-1) | Italie F | ||
| FT | Espagne F | 5-0 (4-0) | Portugal F |
| FT | Aris Thessaloniki FC | 1-3 (1-2) | Livingston | ||
| FT | Rubin Kazan | 1-0 (1-0) | FC Yenisey Krasnoyarsk | ||
| FT | Young Boys | 4-1 (2-1) | Kriens | ||
| FT | Zenit St. Petersburg | 2-0 (0-0) | Dynamo Makhachkala | ||
| FT | SC Heerenveen | 4-5 (2-3) | Almere City FC | ||
| FT | Baronie | 0-5 (0-1) | NAC Breda |
| FT | Maxline Vitebsk | 2-0 (2-0) | Dinamo Minsk |
