| FT | CF Montreal | 1-0 (1-0) | New York City FC | ||
| FT | DC United | 0-1 (0-1) | Nashville SC | ||
| FT | New England Revolution | 3-3 (0-2) | Colorado Rapids | ||
| FT | New York Red Bulls | 2-2 (1-2) | Minnesota United | ||
| FT | Orlando City | 1-2 (0-1) | FC Cincinnati | ||
| FT | Toronto FC | 3-0 (1-0) | Portland Timbers | ||
| FT | Chicago Fire FC | 3-2 (3-0) | Charlotte FC | ||
| FT | FC Dallas | 2-3 (1-1) | San Diego FC | ||
| FT | Houston Dynamo FC | 1-0 (0-0) | St. Louis City | ||
| FT | Sporting Kansas City | 1-1 (0-1) | Real Salt Lake | ||
| FT | San Jose Earthquakes | 1-1 (1-0) | LA Galaxy | ||
| FT | Seattle Sounders FC | 2-0 (1-0) | Austin FC | ||
| FT | Columbus Crew | 1-0 (1-0) | Philadelphia Union | ||
| FT | Los Angeles FC | 0-1 (0-1) | Vancouver Whitecaps |
| FT | Independiente Medellin | 1-2 (1-1) | Santa Fe |
| FT | Barcelona SC | 3-3 (2-0) | Libertad | ||
| FT | Orense | 2-1 (1-0) | LDU de Quito | ||
| FT | Tecnico Universitario | 0-0 (0-0) | El Nacional | ||
| FT | Universidad Catolica | 0-3 (0-3) | Independiente del Valle | ||
| FT | CSD Macara | 1-1 (0-1) | Emelec |
| FT | Gimnasia Mendoza | 1-2 (1-0) | Independiente |
| FT | Paris St-Germain | 4-0 (4-0) | Inter Miami CF | ||
| FT | Flamengo | 2-4 (1-3) | Bayern Munich |
| FT | Fram Reykjavik | 2-0 (2-0) | IBV Vestmannaeyjar | ||
| FT | Vestri | 0-2 (0-0) | IA Akranes | ||
| FT | KR Reykjavik | 3-2 (0-1) | FH Hafnarfjordur | ||
| FT | Vikingur Reykjavik | 2-1 (0-0) | Afturelding |
| FT | Australie F | 1-1 (0-0) | Slovénie F | ||
| FT | Nigeria F | 3-1 (2-0) | Ghana F | ||
| FT | Algérie F | 1-0 (1-0) | DR Congo | ||
| FT | Angleterre F | 7-0 (3-0) | Jamaïque F | ||
| FT | Etats-Unis F | 4-0 (2-0) | Irlande F |
| FT | FK Haugesund | 0-0 (0-0) | Kristiansund BK | ||
| FT | Bodoe/Glimt | 1-2 (1-1) | Sarpsborg 08 | ||
| FT | Bryne | 1-1 (0-1) | Hamarkameratene | ||
| FT | Fredrikstad | 0-1 (0-1) | Tromsoe | ||
| FT | Molde | 2-3 (0-2) | KFUM | ||
| FT | Stroemsgodset | 0-2 (0-1) | Vaalerenga |
| FT | Spartak Moscow | 3-1 (1-1) | Torpedo Moscow | ||
| FT | Go Ahead Eagles | 2-0 (1-0) | Sportfreunde Lotte | ||
| FT | Vejle Boldklub | 3-3 (3-0) | Esbjerg fB | ||
| FT | Zenit St. Petersburg | 3-0 (1-0) | FK Crvena Zvezda |
| FT | Naftan Novopolotsk | 2-2 (1-1) | BATE Borisov | ||
| FT | FK Slutsk | 0-3 (0-3) | Arsenal Dzerzhinsk |
| FT | Harju Jalgpallikool | 1-1 (0-1) | FC Kuressaare | ||
| FT | Flora Tallinn | 3-1 (0-0) | Talinna Kalev |
| FT | Riteriai | 0-2 (0-2) | Dainava Alytus | ||
| FT | FA Siauliai | 5-0 (2-0) | Dziugas Telsiai | ||
| FT | FK Panevezys | 2-4 (2-2) | Zalgiris Vilnius |
| FT | AIK | 3-0 (2-0) | IFK Göteborg | ||
| FT | Degerfors | 0-3 (0-1) | Brommapojkarna | ||
| FT | Haecken | 1-3 (0-2) | GAIS | ||
| FT | IFK Vaernamo | 0-0 (0-0) | Elfsborg |
| FT | Changchun Yatai | 1-2 (0-2) | Shanghai Shenhua | ||
| FT | Qingdao West Coast | 1-0 (1-0) | Qingdao Hainiu | ||
| FT | Meizhou Hakka | 1-2 (0-2) | Tianjin Jinmen Tiger | ||
| FT | Wuhan Three Towns | 2-2 (1-1) | Chengdu Rongcheng FC |
| FT | Yanbian Longding | 1-0 (0-0) | Nantong Zhiyun FC | ||
| FT | Guangdong GZ-Power | 0-0 (0-0) | Qingdao Red Lions | ||
| FT | Shijiazhuang Gongfu | 2-2 (2-1) | Foshan Nanshi |
| FT | Cheongju FC | 2-2 (1-0) | Jeonnam Dragons | ||
| FT | Gimpo FC | 1-1 (1-0) | Incheon United | ||
| FT | Suwon Samsung Bluewings | 1-1 (1-0) | Busan I'Park |
| FT | FC Seoul | 4-1 (3-0) | Pohang Steelers |
| FT | Albirex Niigata | 0-4 (0-1) | Machida Zelvia | ||
| FT | Tokyo Verdy | 1-0 (1-0) | Kawasaki Frontale |
