| FT | St. Louis City | 2-1 (1-0) | San Jose Earthquakes | ||
| FT | Nashville SC | 2-2 (2-0) | New York City FC | ||
| FT | CF Montreal | 0-3 (0-0) | New England Revolution | ||
| FT | FC Cincinnati | 1-2 (1-2) | DC United | ||
| FT | Inter Miami CF | 5-1 (3-0) | Columbus Crew | ||
| FT | New York Red Bulls | 2-0 (2-0) | Atlanta United | ||
| FT | Orlando City | 1-3 (1-3) | Chicago Fire FC | ||
| FT | Toronto FC | 0-2 (0-0) | Charlotte FC | ||
| FT | FC Dallas | 0-0 (0-0) | Philadelphia Union | ||
| FT | Houston Dynamo FC | 1-3 (1-1) | Sporting Kansas City | ||
| FT | LA Galaxy | 2-0 (1-0) | Real Salt Lake | ||
| FT | San Diego FC | 2-0 (0-0) | Austin FC |
| FT | Junior FC | 1-1 (1-1) | Tolima | ||
| FT | Independiente Medellin | 1-1 (0-0) | America de Cali |
| FT | Trinidad etT. | 0-4 (0-3) | Ghana | ||
| Pen. | Jamaïque | 2-2(2-2) | Nigéria* | ||
| FT | Grenada | 2-0 (1-0) | Anguilla | ||
| FT | Salvador | 1-1 (0-1) | Guatemala |
| FT | Brésil F | 3-1 (2-0) | Japon F | ||
| FT | Mexique F | 2-2 (1-0) | Uruguay F | ||
| FT | Malaisie F | 1-2 (1-1) | Hong-Kong F | ||
| FT | Zambie F | 1-1 (0-0) | Botswana F | ||
| FT | Bangladesh F | 0-0 (0-0) | Indonésie F | ||
| FT | Nlle Zélande F | 1-3 (1-2) | Venezuela F | ||
| FT | Canada F | 4-1 (2-0) | Haïti F | ||
| FT | Etats-Unis F | 3-0 (2-0) | Chine F | ||
| FT | Guatemala F | 1-2 (0-1) | Puerto Rico F |
| FT | Bahia | 2-1 (0-0) | Sao Paulo | ||
| FT | Vasco da Gama | 0-2 (0-2) | Red Bull Bragantino |
| FT | CSD Macara | 2-2 (0-0) | Manta | ||
| FT | LDU de Quito | 3-2 (2-2) | Tecnico Universitario | ||
| FT | Delfin | 1-1 (0-1) | Independiente del Valle | ||
| FT | Emelec | 1-0 (0-0) | Orense |
| FT | Huachipato | 0-1 (0-0) | CD Nublense | ||
| FT | La Serena | 2-4 (1-2) | Coquimbo Unido | ||
| FT | Universidad de Chile | 6-0 (3-0) | O'Higgins | ||
| FT | Everton CD | 1-1 (0-0) | Audax Italiano |
| FT | Atletico Tembetary | 1-6 (1-3) | Cerro Porteno |
| FT | Paris St-Germain | 5-0 (2-0) | Inter Milan |
| FT | Torpedo Zhodino | 3-2 (2-0) | BATE Borisov | ||
| FT | Neman Grodno | 1-2 (1-1) | Slavia Mozyr | ||
| FT | Dinamo Minsk | 1-0 (0-0) | Naftan Novopolotsk | ||
| FT | Maxline Vitebsk | 2-0 (0-0) | FK Vitebsk |
| FT | Stroemsgodset | 0-3 (0-1) | Hamarkameratene | ||
| FT | Tromsoe | 2-1 (0-0) | Vaalerenga |
| FT | Racing de Ferrol | 0-2 (0-1) | Sporting Gijon | ||
| FT | Malaga | 2-2 (0-1) | Burgos CF |
| FT | Wydad Casablanca | 0-1 (0-1) | FC Porto |
| FT | FC KTP | 2-2 (0-1) | IFK Mariehamn | ||
| FT | AC Oulu | 2-2 (0-0) | SJK | ||
| FT | Haka | 2-1 (1-0) | VPS | ||
| FT | HJK | 0-0 (0-0) | KuPS |
| FT | Riga FC | 3-0 (1-0) | FK Tukums 2000 | ||
| FT | RFS | 6-0 (4-0) | Grobina |
| FT | Fenerbahce | 2-1 (0-1) | Konyaspor | ||
| FT | Çaykur Rizespor | 5-2 (1-0) | Hatayspor | ||
| FT | Adana Demirspor | 2-2 (2-1) | Gaziantep FK | ||
| FT | Alanyaspor | 2-0 (1-0) | Sivasspor |
| Pen. | *Arda Kardzhali | 1-1(1-1) | PFK CSKA Sofia |
| FT | FK Velez Mostar | 3-0 (2-0) | Sloga Doboj | ||
| FT | Posusje | 1-2 (1-1) | FK Sarajevo | ||
| FT | Radnik Bijeljina | 1-2 (0-0) | Zeljeznicar |
| FT | Dziugas Telsiai | 1-1 (1-1) | Zalgiris Vilnius | ||
| FT | Hegelmann | 2-0 (0-0) | Banga Gargzdai |
| FT | Harju Jalgpallikool | 0-1 (0-1) | FCI Levadia | ||
| FT | Paide Linnameeskond | 0-1 (0-1) | Narva Trans |
| FT | Degerfors | 1-2 (1-2) | Oesters IF | ||
| FT | Elfsborg | 0-2 (0-0) | Hammarby | ||
| FT | IFK Norrkoeping | 0-3 (0-1) | GAIS |
| FT | Liaoning Tieren | 1-0 (0-0) | Shijiazhuang Gongfu | ||
| FT | Foshan Nanshi | 1-1 (1-1) | Chongqing Tongliang Long | ||
| FT | Guangxi Pingguo | 1-0 (1-0) | Qingdao Red Lions | ||
| FT | Nanjing City FC | 2-4 (1-0) | Guangdong GZ-Power |
| FT | Jeonnam Dragons | 3-2 (2-1) | Hwaseong FC | ||
| FT | Seoul E-Land FC | 1-4 (0-1) | Busan I'Park | ||
| FT | Ansan Greeners | 1-0 (1-0) | Seongnam FC | ||
| FT | Cheongju FC | 1-2 (1-0) | Gyeongnam FC |
| FT | FC Anyang | 1-1 (0-1) | Daejeon Hana Citizen | ||
| FT | FC Seoul | 1-3 (0-1) | Jeju SK | ||
| FT | Jeonbuk Hyundai Motors FC | 3-1 (1-1) | Ulsan HD FC |
| FT | Avispa Fukuoka | 0-0 (0-0) | Tokyo Verdy | ||
| FT | Machida Zelvia | 0-3 (0-2) | Yokohama F.Marinos | ||
| FT | Nagoya Grampus | 3-0 (0-0) | Albirex Niigata | ||
| FT | Kashiwa Reysol | 1-3 (1-2) | Vissel Kobe | ||
| FT | Sanfrecce Hiroshima | 1-2 (0-0) | Kawasaki Frontale | ||
| FT | Gamba Osaka | 0-1 (0-1) | Kashima Antlers | ||
| FT | Kyoto Sanga FC | 3-0 (1-0) | FC Tokyo |
| FT | Melbourne City FC | 1-0 (1-0) | Melbourne Victory |
