| FT | Gremio | 0-0 (0-0) | CS Alagoano | ||
| FT | Nautico | 1-2 (0-1) | Sao Paulo | ||
| Pen. | Fortaleza | 1-1(1-1) | Retro FC* | ||
| FT | Aparecidense | 1-4 (1-2) | Fluminense | ||
| FT | Bahia | 4-0 (3-0) | Paysandu | ||
| FT | Atletico MG | 4-0 (1-0) | Maringa FC | ||
| FT | Corinthians | 1-0 (0-0) | Novorizontino | ||
| FT | Flamengo | 4-2 (3-1) | Botafogo PB |
| FT | Lanus | 2-0 (2-0) | Velez Sarsfield |
| FT | General Caballero JLM | 1-1 (0-0) | 2 de Mayo | ||
| FT | Atletico Tembetary | 1-2 (0-1) | Guarani | ||
| FT | Olimpia | 1-1 (0-1) | Libertad | ||
| FT | Sportivo Ameliano | 0-0 (0-0) | Cerro Porteno |
| FT | Tottenham Hotspur | 1-0 (1-0) | Manchester United |
| FT | Catanzaro | 0-2 (0-0) | Spezia | ||
| FT | Juve Stabia | 2-1 (1-0) | Cremonese |
| FT | Metz | 1-1 (1-0) | Reims |
| FT | Al Nassr FC | 2-0 (0-0) | Al Khaleej | ||
| FT | Al Kholood | 2-0 (1-0) | Al-Fayha | ||
| FT | Al-Wehda | 1-1 (0-0) | Al Hilal |
| FT | Eintracht Rheine | 2-4 (2-3) | Borussia Moenchengladbach | ||
| FT | SC Weimar | 1-7 (0-2) | Eintracht Frankfurt | ||
| FT | Meppen | 4-1 (1-0) | Werder Bremen |
| FT | Grobina | 2-0 (1-0) | FK Tukums 2000 | ||
| FT | SK Super Nova | 0-0 (0-0) | FK Jelgava |
| FT | FC Dordrecht | 2-1 (2-1) | Willem II |
| FT | FC Gagra | 1-1 (0-1) | FC Gareji 1960 | ||
| FT | FC Telavi | 1-2 (1-1) | Dinamo Batumi |
| FT | Ilves | 3-0 (0-0) | KuPS |
| FT | Shenzhen Juniors | 1-5 (0-2) | Dalian Yingbo | ||
| FT | Yanbian Longding | 0-2 (0-0) | Qingdao West Coast | ||
| FT | Dingnan United | 1-2 (0-0) | Yunnan Yukun | ||
| FT | Wuxi Wugo | 0-3 (0-2) | Shanghai Shenhua | ||
| Pen. | *Guangdong GZ-Power | 2-2(2-2) | Shenzhen Peng City | ||
| Pen. | *Dalian Kuncheng | 1-1(1-1) | Changchun Yatai | ||
| Pen. | Liaoning Tieren | 0-0(0-0) | Qingdao Hainiu* | ||
| FT | Chongqing Tongliang Long | 1-2 (0-2) | Henan FC | ||
| FT | Guangxi Pingguo | 0-3 (0-1) | Chengdu Rongcheng FC | ||
| FT | Qingdao Red Lions | 0-5 (0-2) | Shandong Taishan | ||
| FT | Shijiazhuang Gongfu | 0-5 (0-2) | Beijing Guoan | ||
| FT | Suzhou Dongwu | 2-6 (1-1) | Shanghai Port | ||
| FT | Guizhou Zhucheng Athletic | 0-1 (0-1) | Tianjin Jinmen Tiger |
| FT | Kawasaki Frontale | 2-2 (1-1) | Urawa Red Diamonds | ||
| FT | Yokohama F.Marinos | 1-2 (1-1) | Vissel Kobe |
