| FT | CF Montreal | 1-6 (0-3) | Toronto FC | ||
| FT | New York City FC | 2-0 (1-0) | New York Red Bulls | ||
| FT | Columbus Crew | 1-1 (0-1) | FC Cincinnati | ||
| FT | Atlanta United | 0-1 (0-0) | Philadelphia Union | ||
| FT | Charlotte FC | 1-4 (0-1) | Chicago Fire FC | ||
| FT | New England Revolution | 0-0 (0-0) | San Jose Earthquakes | ||
| FT | Austin FC | 0-0 (0-0) | Vancouver Whitecaps | ||
| FT | Minnesota United | 3-0 (1-0) | St. Louis City | ||
| FT | Nashville SC | 0-0 (0-0) | DC United | ||
| FT | FC Dallas | 0-2 (0-0) | Houston Dynamo FC | ||
| FT | Colorado Rapids | 1-0 (0-0) | Real Salt Lake | ||
| FT | Portland Timbers | 1-1 (1-1) | Seattle Sounders FC | ||
| FT | San Diego FC | 0-0 (0-0) | Sporting Kansas City |
| FT | Millonarios | 1-0 (1-0) | Envigado | ||
| FT | La Equidad | 1-4 (0-4) | Bucaramanga | ||
| FT | Deportivo Cali | 0-2 (0-1) | Santa Fe | ||
| FT | Chico FC | 2-1 (1-0) | Alianza FC |
| FT | Toluca | 3-0 (1-0) | Tigres |
| FT | Ceara | 2-0 (1-0) | Sport Recife | ||
| FT | Vasco da Gama | 3-0 (1-0) | Fortaleza | ||
| FT | Sao Paulo | 2-1 (0-1) | Gremio |
| FT | Deportivo Cuenca | 2-0 (2-0) | Tecnico Universitario | ||
| FT | Aucas | 1-1 (0-0) | Manta | ||
| FT | Mushuc Runa | 2-5 (2-2) | Orense | ||
| FT | CSD Macara | 1-1 (0-1) | El Nacional |
| FT | Nacional | 4-0 (4-0) | Luqueno | ||
| FT | Libertad | 1-1 (0-0) | Sportivo Trinidense |
| FT | Union La Calera | 0-1 (0-0) | Coquimbo Unido | ||
| FT | Cobresal | 0-1 (0-1) | Audax Italiano | ||
| FT | O'Higgins | 2-0 (1-0) | Universidad Catolica |
| FT | RSB Berkane | 2-0 (2-0) | Simba SC |
| FT | Deportivo La Coruna | 2-3 (0-2) | Granada CF | ||
| FT | Eibar | 1-0 (1-0) | Burgos CF | ||
| FT | Cartagena | 1-0 (1-0) | Tenerife | ||
| FT | SD Huesca | 2-1 (0-1) | Elche | ||
| FT | Malaga | 2-1 (0-0) | Sporting Gijon |
| FT | Lens | 4-0 (1-0) | Monaco | ||
| FT | Lille | 2-1 (1-0) | Reims | ||
| FT | Lyon | 2-0 (0-0) | Angers | ||
| FT | Marseille | 4-2 (3-1) | Rennes | ||
| FT | Nantes | 3-0 (2-0) | Montpellier | ||
| FT | Nice | 6-0 (3-0) | Brest | ||
| FT | Paris St-Germain | 3-1 (0-1) | Auxerre | ||
| FT | St-Etienne | 2-3 (1-2) | Toulouse | ||
| FT | Strasbourg | 2-3 (1-1) | Le Havre |
| FT | Cosmos | 4-2 (2-2) | San Giovanni | ||
| FT | La Fiorita Montegiardino | 1-0 (1-0) | Tre Fiori |
| FT | Royal Antwerp | 0-4 (0-3) | Union St.Gilloise |
| FT | Genoa | 2-3 (1-0) | Atalanta |
| FT | Saint-Gall | 3-2 (2-1) | FC Zürich | ||
| FT | Winterthur | 2-2 (1-2) | Yverdon | ||
| FT | Sion | 2-1 (0-0) | Grasshopper Zurich |
| FT | Longford Town | 0-0 (0-0) | Finn Harps |
| FT | JS Kabylie | 1-2 (1-2) | JS Saoura | ||
| FT | Paradou AC | 3-1 (2-0) | USM Alger |
| FT | Pogon Szczecin | 3-3 (2-2) | Lechia Gdansk | ||
| FT | Piast Gliwice | 2-0 (1-0) | Gornik Zabrze | ||
| FT | Korona Kielce | 1-1 (1-0) | Rakow Czestochowa |
| Abd. | ADO La Haye | 0-1 (0-0) | Telstar | ||
| FT | FC Dordrecht | 2-0 (0-0) | De Graafschap |
| FT | Al-Ettifaq | 0-0 (0-0) | Damac FC | ||
| FT | Al-Fayha | 2-0 (0-0) | Al Akhdoud | ||
| FT | Al Ahli | 4-1 (0-0) | Al Kholood |
| FT | Zalaegerszegi TE | 0-0 (0-0) | Gyori ETO | ||
| FT | Diosgyori VTK | 2-1 (0-1) | MTK Budapest |
| FT | Catanzaro | 1-0 (0-0) | Cesena | ||
| FT | Juve Stabia | 1-0 (0-0) | Palermo |
| FT | Hapoel Haifa | 1-1 (1-0) | Maccabi Netanya |
| FT | NK Varazdin | 2-1 (2-1) | Osijek | ||
| FT | NK Lokomotiva | 1-1 (0-1) | Dinamo Zagreb |
| FT | Levski Sofia | 2-2 (0-1) | Ludogorets Razgrad |
| FT | FCSB | 1-0 (1-0) | Universitatea Craiova |
| FT | AVS Futebol SAD | 0-3 (0-2) | Moreirense | ||
| FT | Arouca | 4-1 (3-1) | Boavista | ||
| FT | Braga | 1-1 (1-0) | Benfica | ||
| FT | Estoril | 4-0 (4-0) | Estrela da Amadora | ||
| FT | FC Porto | 3-0 (1-0) | Nacional | ||
| FT | Farense | 1-2 (1-1) | Santa Clara | ||
| FT | Sporting CP | 2-0 (0-0) | Vitoria de Guimaraes |
| FT | Mladost Lucani | 0-4 (0-2) | Partizan Beograd | ||
| FT | Novi Pazar | 3-3 (1-1) | FK Crvena Zvezda | ||
| FT | TSC Backa Topola | 3-2 (2-2) | OFK Beograd | ||
| FT | Vojvodina | 0-0 (0-0) | FK Radnicki 1923 |
| FT | Sloga Doboj | 4-1 (4-1) | Sloboda Tuzla | ||
| FT | Igman Konjic | 1-2 (0-0) | GOSK Gabela | ||
| FT | Posusje | 1-2 (0-1) | Zrinjski Mostar |
| FT | Standard Liege | 0-0 (0-0) | FCV Dender EH |
| FT | AC Oulu | 0-1 (0-0) | IFK Mariehamn | ||
| FT | FC Inter Turku | 3-1 (1-1) | Ilves | ||
| FT | HJK | 4-1 (1-1) | FC KTP | ||
| FT | VPS | 0-0 (0-0) | FF Jaro |
| FT | FK Slutsk | 1-1 (1-0) | Isloch | ||
| FT | Dynamo Brest | 5-0 (3-0) | FC Minsk | ||
| FT | Dinamo Minsk | 3-2 (2-1) | FK Molodechno |
| FT | Adana Demirspor | 0-5 (0-3) | Hatayspor |
| FT | FC Orenburg | 1-2 (1-1) | FC Krasnodar | ||
| FT | Khimki | 3-2 (1-1) | Rubin Kazan | ||
| FT | Nizhny Novgorod | 1-1 (0-1) | Fakel |
| FT | Crystal Palace | 1-0 (1-0) | Manchester City |
| FT | Olimpija Ljubljana | 5-0 (2-0) | Radomlje | ||
| FT | Primorje | 2-0 (1-0) | Mura |
| FT | Metz | 1-0 (0-0) | Dunkerque |
| FT | Pardubice | 2-1 (1-1) | Mlada Boleslav | ||
| FT | SK Dynamo Ceske Budejovice | 0-3 (0-1) | Teplice | ||
| FT | Slovacko | 3-2 (0-1) | Dukla Praha |
| FT | Altach | 0-0 (0-0) | SK Austria Klagenfurt | ||
| FT | Grazer AK | 1-0 (0-0) | LASK | ||
| FT | Hartberg | 3-2 (0-1) | WSG Tirol |
| FT | Slovan Bratislava | 1-0 (1-0) | FC Kosice | ||
| FT | Spartak Trnava | 2-1 (0-1) | Zeleziarne Podbrezova | ||
| FT | Zilina | 0-1 (0-0) | DAC 1904 Dunajska Streda |
| FT | Dukla Banska Bystrica | 2-3 (1-2) | Zemplin Michalovce | ||
| FT | Komarno | 1-2 (1-0) | Ruzomberok | ||
| FT | Trencin | 2-0 (2-0) | Skalica |
| FT | FC Kolos Kovalivka | 2-1 (0-1) | Karpaty | ||
| FT | Kryvbas | 1-0 (0-0) | Obolon Kyiv | ||
| FT | Zorya | 0-1 (0-1) | Polissya Zhytomyr |
| FT | PFK CSKA Sofia | 2-1 (1-1) | Beroe |
| FT | Hegelmann | 1-0 (1-0) | Dziugas Telsiai | ||
| FT | FK Panevezys | 3-0 (2-0) | Riteriai | ||
| FT | FK Kauno Zalgiris | 3-0 (2-0) | Zalgiris Vilnius |
| FT | Ballkani | 0-1 (0-1) | Llapi | ||
| FT | Dukagjini | 3-1 (2-0) | Ferizaj | ||
| FT | Feronikeli | 0-1 (0-0) | FC Prishtina | ||
| FT | Gjilani | 0-0 (0-0) | Drita | ||
| FT | Malisheva | 1-2 (0-0) | Suhareka |
| FT | Parnu JK Vaprus | 2-1 (1-0) | Tammeka | ||
| FT | Paide Linnameeskond | 2-2 (1-1) | Harju Jalgpallikool |
| FT | Augsburg | 1-2 (1-0) | Union Berlin | ||
| FT | Borussia Dortmund | 3-0 (1-0) | Holstein Kiel | ||
| FT | Borussia Moenchengladbach | 0-1 (0-0) | VFL Wolfsburg | ||
| FT | FC Heidenheim | 1-4 (0-2) | Werder Bremen | ||
| FT | Freiburg | 1-3 (1-1) | Eintracht Frankfurt | ||
| FT | Hoffenheim | 0-4 (0-1) | Bayern Munich | ||
| FT | Mainz 05 | 2-2 (1-0) | Bayer Leverkusen | ||
| FT | RB Leipzig | 2-3 (2-1) | VfB Stuttgart | ||
| FT | St. Pauli | 0-2 (0-1) | VFL Bochum |
| FT | Shamakhi FK | 0-1 (0-1) | Araz PFK | ||
| FT | Sumqayit | 0-1 (0-1) | Turan Tovuz | ||
| FT | Zira | 1-1 (1-0) | Sabah FK |
| FT | FC Porto B | 1-4 (0-1) | Benfica B | ||
| FT | Academico Viseu | 0-1 (0-1) | Pacos de Ferreira | ||
| FT | Felgueiras 1932 | 2-1 (0-1) | Oliveirense |
| FT | Dalian Yingbo | 0-3 (0-2) | Shanghai Shenhua | ||
| FT | Changchun Yatai | 1-2 (0-1) | Tianjin Jinmen Tiger | ||
| FT | Chengdu Rongcheng FC | 1-1 (1-1) | Qingdao West Coast | ||
| FT | Qingdao Hainiu | 1-1 (0-0) | Beijing Guoan | ||
| FT | Shanghai Port | 1-1 (0-0) | Shandong Taishan |
| FT | Celtic | 1-1 (0-0) | St. Mirren | ||
| FT | Dundee United | 2-1 (0-1) | Aberdeen | ||
| FT | Hibernian | 2-2 (1-1) | Rangers |
| FT | Dingnan United | 3-3 (1-1) | Liaoning Tieren | ||
| FT | Shaanxi Union | 3-2 (0-2) | Nantong Zhiyun FC | ||
| FT | Chongqing Tongliang Long | 1-0 (0-0) | Yanbian Longding | ||
| FT | Guangdong GZ-Power | 2-0 (0-0) | Shanghai Jiading | ||
| FT | Shijiazhuang Gongfu | 0-2 (0-1) | Qingdao Red Lions |
| FT | UTA Arad | 0-0 (0-0) | FC Gloria Buzau |
| FT | Bucheon FC 1995 | 1-0 (0-0) | Hwaseong FC | ||
| FT | Gyeongnam FC | 1-3 (0-2) | Chungnam Asan FC | ||
| FT | Busan I'Park | 1-4 (1-3) | Suwon Samsung Bluewings | ||
| FT | Cheonan City | 1-1 (1-1) | Seongnam FC |
| FT | Jeonbuk Hyundai Motors FC | 2-0 (2-0) | FC Anyang | ||
| FT | Gangwon FC | 1-1 (0-0) | Ulsan HD FC | ||
| FT | Gimcheon Sangmu | 1-1 (0-0) | Jeju SK |
| FT | Melbourne Victory | 0-1 (0-0) | Auckland FC |
| FT | Machida Zelvia | 3-0 (3-0) | Kashiwa Reysol | ||
| FT | Sanfrecce Hiroshima | 2-1 (0-0) | Tokyo Verdy | ||
| FT | Vissel Kobe | 3-2 (0-0) | Gamba Osaka | ||
| FT | Yokohama F.Marinos | 0-3 (0-1) | Kyoto Sanga FC | ||
| FT | Avispa Fukuoka | 1-1 (0-0) | Nagoya Grampus | ||
| FT | Kashima Antlers | 1-0 (1-0) | Shimizu S-Pulse | ||
| FT | Shonan Bellmare | 0-1 (0-1) | Yokohama FC | ||
| FT | Urawa Red Diamonds | 3-2 (1-1) | FC Tokyo |
