| FT | Inter Miami CF | 1-3 (1-0) | Vancouver Whitecaps | ||
| FT | Cruz Azul | 1-0 (0-0) | Tigres |
| FT | CS Alagoano | 3-2 (1-1) | Gremio | ||
| FT | Novorizontino | 0-1 (0-1) | Corinthians | ||
| FT | Paysandu | 0-1 (0-1) | Bahia | ||
| FT | Brusque | 0-0 (0-0) | Athletico Paranaense | ||
| FT | Operario Ferroviario | 1-1 (0-1) | Vasco da Gama | ||
| FT | Santos FC | 1-1 (1-0) | CRB | ||
| FT | Criciuma | 1-0 (0-0) | Red Bull Bragantino | ||
| FT | Botafogo PB | 0-1 (0-0) | Flamengo | ||
| FT | Cruzeiro | 2-0 (2-0) | Vila Nova |
| FT | RSB Berkane | 1-1 (1-0) | Difaa El Jadida |
| FT | Djurgaarden | 1-4 (0-2) | Chelsea | ||
| FT | Real Betis | 2-1 (1-0) | Fiorentina |
| FT | Athletic Bilbao | 0-3 (0-3) | Manchester United | ||
| FT | Tottenham Hotspur | 3-1 (2-0) | Bodoe/Glimt |
| FT | Llaneros FC | 0-1 (0-0) | Santa Fe | ||
| FT | Envigado | 1-2 (1-1) | Once Caldas |
| FT | Nottingham | 0-2 (0-1) | Brentford |
| FT | Al Akhdoud | 1-2 (0-0) | Al-Wehda | ||
| FT | Al Riyadh | 2-4 (2-1) | Al-Orobah FC | ||
| FT | Al Fateh FC | 3-1 (3-1) | Al Shabab |
| FT | Juve Stabia | 2-0 (2-0) | Catanzaro | ||
| FT | Cosenza | 1-0 (1-0) | Bari | ||
| FT | Mantova | 3-0 (1-0) | Cesena | ||
| FT | Modena | 2-3 (2-1) | AC Reggiana 1919 | ||
| FT | Palermo | 1-2 (1-0) | Sudtirol | ||
| FT | Pisa | 1-0 (0-0) | Frosinone | ||
| FT | Sampdoria | 0-0 (0-0) | Cremonese | ||
| FT | Spezia | 2-0 (1-0) | Salernitana | ||
| FT | Cittadella | 0-1 (0-1) | Brescia | ||
| FT | Sassuolo | 2-0 (1-0) | Carrarese |
| FT | Hebar | 1-3 (0-2) | Krumovgrad |
| FT | SK Super Nova | 1-5 (0-2) | Riga FC | ||
| FT | RFS | 1-0 (1-0) | Auda |
| FT | Rosenborg | 1-1 (0-0) | Kristiansund BK |
| FT | Royal Antwerp | 1-3 (0-0) | Anderlecht | ||
| FT | Club Brugge | 4-1 (1-1) | La Gantoise |
| FT | Dalian Yingbo | 3-2 (2-0) | Yunnan Yukun | ||
| FT | Shenzhen Peng City | 1-0 (1-0) | Tianjin Jinmen Tiger | ||
| FT | Henan FC | 1-2 (0-0) | Wuhan Three Towns | ||
| FT | Zhejiang Professional | 4-2 (3-1) | Changchun Yatai | ||
| FT | Shandong Taishan | 1-1 (0-0) | Qingdao Hainiu | ||
| FT | Shanghai Port | 1-2 (1-1) | Beijing Guoan |
| FT | Zabbar St. Patrick | 2-2 (2-0) | Hibernians |
| FT | Atletico Tucuman | 2-0 (1-0) | Independiente |
