| FT | Busan I'Park | 0-1 (0-0) | Gyeongnam FC | ||
| FT | Hwaseong FC | 1-1 (0-1) | Chungnam Asan FC | ||
| FT | Cheonan City | 1-2 (0-0) | Bucheon FC 1995 | ||
| FT | Seongnam FC | 1-1 (1-1) | Cheongju FC |
| FT | Daejeon Hana Citizen | 1-0 (0-0) | Suwon FC | ||
| FT | Gangwon FC | 0-0 (0-0) | Jeju SK | ||
| FT | FC Seoul | 0-0 (0-0) | Gimcheon Sangmu |
| FT | Leon | 2-1 (1-1) | Tijuana | ||
| FT | Necaxa | 1-2 (0-0) | Tigres | ||
| FT | Club Universidad Nacional | 0-1 (0-0) | CD Guadalajara | ||
| FT | Queretaro FC | 2-0 (1-0) | Puebla | ||
| FT | Atlas | 3-1 (0-1) | Atletico de San Luis | ||
| FT | Monterrey | 4-2 (1-1) | Santos Laguna |
| FT | New England Revolution | 0-1 (0-0) | Columbus Crew | ||
| FT | New York Red Bulls | 2-0 (2-0) | Nashville SC | ||
| FT | Orlando City | 4-2 (2-0) | Toronto FC | ||
| FT | Philadelphia Union | 4-1 (2-0) | FC Cincinnati | ||
| FT | Chicago Fire FC | 2-2 (1-1) | DC United | ||
| FT | Minnesota United | 1-0 (0-0) | CF Montreal | ||
| FT | Sporting Kansas City | 1-2 (1-2) | San Jose Earthquakes | ||
| FT | Colorado Rapids | 3-3 (2-2) | FC Dallas | ||
| FT | Los Angeles FC | 1-0 (0-0) | New York City FC | ||
| FT | Portland Timbers | 1-0 (0-0) | Austin FC | ||
| FT | San Diego FC | 0-0 (0-0) | St. Louis City | ||
| FT | Vancouver Whitecaps | 2-1 (1-1) | LA Galaxy | ||
| FT | Houston Dynamo FC | 1-4 (0-3) | Inter Miami CF |
| FT | Huachipato | 2-1 (0-0) | Colo Colo | ||
| FT | Cobresal | 2-1 (0-0) | Universidad de Chile | ||
| FT | Union La Calera | 2-2 (1-1) | O'Higgins |
| FT | Libertad | 1-4 (0-2) | Barcelona SC | ||
| FT | Independiente del Valle | 1-1 (1-0) | Universidad Catolica | ||
| FT | Aucas | 2-2 (2-1) | Vinotinto del Ecuador | ||
| FT | El Nacional | 0-0 (0-0) | Tecnico Universitario |
| FT | America de Cali | 2-0 (1-0) | Deportivo Pereira | ||
| FT | Once Caldas | 1-2 (1-1) | Alianza FC | ||
| FT | Millonarios | 2-0 (1-0) | Tolima |
| FT | 2 de Mayo | 1-1 (1-0) | Sportivo Trinidense | ||
| FT | Cerro Porteno | 0-1 (0-0) | Guarani |
| FT | Talleres | 1-2 (1-1) | Tigre | ||
| FT | Union | 1-0 (0-0) | Gimnasia LP | ||
| FT | Argentinos Juniors | 2-0 (0-0) | Instituto | ||
| FT | Independiente Rivadavia | 1-1 (0-0) | Lanus | ||
| FT | Velez Sarsfield | 0-2 (0-1) | Huracan |
| FT | Boavista | 1-0 (0-0) | Santa Clara | ||
| FT | Moreirense | 1-1 (0-0) | Estrela da Amadora | ||
| FT | Farense | 0-1 (0-0) | AVS Futebol SAD | ||
| FT | Rio Ave | 2-1 (1-1) | Braga |
| FT | Cordoba | 5-0 (2-0) | Granada CF | ||
| FT | Real Oviedo | 1-2 (1-1) | Deportivo La Coruna | ||
| FT | Albacete | 3-0 (0-0) | Cadiz | ||
| FT | Eldense | 1-2 (1-0) | Levante | ||
| FT | Racing Santander | 2-0 (2-0) | Elche |
| FT | Leganes | 1-0 (0-0) | Getafe | ||
| FT | Barcelona | 4-0 (2-0) | Real Sociedad | ||
| FT | Mallorca | 1-1 (1-0) | Deportivo Alaves | ||
| FT | Osasuna | 3-3 (3-2) | Valencia |
| FT | Monza | 0-2 (0-1) | Torino | ||
| FT | Bologna | 2-1 (0-1) | Cagliari | ||
| FT | Genoa | 1-1 (0-1) | Empoli | ||
| FT | Roma | 2-1 (0-1) | Como | ||
| FT | AC Milan | 1-2 (0-1) | Lazio |
| FT | Lyon | 2-1 (1-1) | Brest | ||
| FT | Angers | 0-4 (0-0) | Toulouse | ||
| FT | Auxerre | 0-1 (0-0) | Strasbourg | ||
| FT | Montpellier | 0-4 (0-1) | Rennes | ||
| FT | Marseille | 2-0 (0-0) | Nantes |
| FT | Al Ittihad | 1-1 (1-0) | Al Akhdoud | ||
| FT | Al Qadsiah | 1-0 (0-0) | Al Riyadh | ||
| FT | Al-Raed | 1-1 (0-0) | Al-Ettifaq |
| FT | Posusje | 1-1 (0-0) | Zeljeznicar | ||
| FT | FK Sarajevo | 1-0 (0-0) | Siroki Brijeg |
| FT | Levadiakos | 1-2 (1-1) | Atromitos | ||
| FT | OFI Crete | 3-0 (1-0) | Lamia | ||
| FT | PAOK Thessaloniki FC | 2-0 (1-0) | Asteras Tripolis | ||
| FT | AEK Athens | 0-1 (0-0) | Olympiacos |
| FT | Genk U23 | 1-2 (1-1) | KSC Lokeren | ||
| FT | Lommel | 2-2 (1-1) | RFC Seraing | ||
| FT | Francs Borains | 1-0 (0-0) | K. Lierse SK |
| FT | Hapoel Haifa | 2-1 (1-1) | Bnei Sakhnin | ||
| FT | Maccabi Petach Tikva | 1-2 (0-1) | Beitar Jerusalem |
| FT | Beerschot | 1-0 (1-0) | KV Mechelen | ||
| FT | Standard Liege | 0-2 (0-0) | Anderlecht | ||
| FT | OH Leuven | 0-0 (0-0) | Westerlo |
| FT | Portimonense | 2-1 (0-1) | Leixoes | ||
| FT | FC Porto B | 0-1 (0-0) | Maritimo | ||
| FT | Uniao de Leiria | 1-0 (1-0) | Penafiel | ||
| FT | Vizela | 5-0 (3-0) | Feirense |
| FT | CSM Politehnica Iasi | 1-0 (1-0) | Petrolul Ploiesti | ||
| FT | Rapid Bucuresti | 0-0 (0-0) | FCSB |
| FT | Çaykur Rizespor | 3-1 (0-0) | Alanyaspor | ||
| FT | Kasimpasa | 3-3 (0-1) | Galatasaray | ||
| FT | Fenerbahce | 3-0 (3-0) | Antalyaspor |
| FT | Slovan Liberec | 1-1 (1-0) | Dukla Praha | ||
| FT | Karvina | 2-0 (0-0) | Slovacko | ||
| FT | Mlada Boleslav | 0-2 (0-1) | Viktoria Plzen | ||
| FT | Slavia Prague | 2-0 (0-0) | Bohemians 1905 |
| FT | Sarpsborg 08 | 0-0 (0-0) | Bryne | ||
| FT | Rosenborg | 0-0 (0-0) | Skeid | ||
| FT | Brann | 1-0 (1-0) | Tromsoe |
| FT | AEK Larnaca | 2-0 (1-0) | Omonia 29 Maiou |
| FT | Debreceni VSC | 1-2 (0-1) | Videoton FC Fehervar | ||
| FT | Kecskemeti TE | 2-2 (1-1) | Paksi SE | ||
| FT | Ferencvarosi TC | 2-2 (0-1) | Gyori ETO |
| FT | Soenderjyske Fodbold | 1-3 (1-1) | Silkeborg | ||
| FT | Viborg | 3-1 (3-0) | Vejle Boldklub | ||
| FT | FC Midtjylland | 2-1 (0-0) | FC Nordsjaelland | ||
| FT | AaB | 0-0 (0-0) | FC Koebenhavn |
| FT | Dinamo Zagreb | 2-2 (1-1) | Hajduk Split | ||
| FT | Sibenik | 0-2 (0-1) | NK Varazdin |
| AP | Newcastle United | AP 1-2 | Brighton & Hove Albion | ||
| Pen. | Manchester United | 1-1(1-1) | Fulham* |
| FT | Union Berlin | 0-1 (0-1) | Holstein Kiel | ||
| FT | Augsburg | 0-0 (0-0) | Freiburg |
| FT | Olimpija Ljubljana | 2-0 (1-0) | NK Celje | ||
| FT | Mura | 1-1 (1-1) | NK Bravo |
| FT | Khimki | 1-0 (1-0) | Fakel | ||
| FT | Spartak Moscow | 2-0 (0-0) | FC Orenburg | ||
| FT | FC Rostov | 1-1 (0-0) | Dinamo Moscow |
| FT | Puszcza Niepolomice | 0-1 (0-1) | Motor Lublin | ||
| FT | Legia Warszawa | 3-1 (1-1) | Slask Wroclaw | ||
| FT | Jagiellonia Bialystok | 1-0 (1-0) | GKS Katowice |
| FT | FK Panevezys | 1-3 (1-2) | FA Siauliai | ||
| FT | Zalgiris Vilnius | 2-1 (1-1) | Dziugas Telsiai |
| FT | Catanzaro | 1-1 (0-1) | AC Reggiana 1919 | ||
| FT | Modena | 1-1 (0-1) | Cosenza | ||
| FT | Palermo | 1-0 (0-0) | Brescia | ||
| FT | Bari | 1-1 (0-1) | Sampdoria |
| FT | Inhulets Petrove | 2-0 (2-0) | Kryvbas | ||
| FT | Zorya | 2-0 (1-0) | Rukh Lviv | ||
| FT | Veres Rivne | 2-1 (1-1) | FC Kolos Kovalivka |
| FT | BW Linz | 2-1 (1-1) | WSG Tirol | ||
| FT | SK Austria Klagenfurt | 1-2 (1-1) | LASK | ||
| FT | Red Bull Salzbourg | 3-1 (0-1) | Sturm Graz |
| FT | OFK Beograd | 2-0 (1-0) | Radnicki Nis | ||
| FT | Tekstilac Odzaci | 1-4 (0-2) | Partizan Beograd | ||
| FT | FK Crvena Zvezda | 4-0 (1-0) | FK IMT Beograd | ||
| FT | Vojvodina | 1-3 (0-1) | FK Spartak Subotica |
| FT | SC Heerenveen | 3-1 (1-0) | AZ Alkmaar | ||
| FT | Almere City FC | 0-1 (0-1) | Ajax Amsterdam | ||
| FT | Heracles | 4-2 (2-2) | PEC Zwolle | ||
| FT | Sparta Rotterdam | 4-0 (1-0) | Willem II |
| FT | Lugano | 0-3 (0-1) | FC Zürich | ||
| FT | Grasshopper Zurich | 1-0 (0-0) | Young Boys | ||
| FT | Yverdon | 2-2 (0-0) | FC Lucerne |
| FT | PFK CSKA Sofia | 2-2 (1-0) | Levski Sofia | ||
| FT | Hebar | 0-1 (0-0) | Cherno More Varna |
| FT | Floriana | 2-2 (0-1) | Mosta | ||
| FT | Hamrun Spartans | 0-1 (0-1) | Gzira United |
| FT | Hibernian | 2-1 (1-1) | Hearts | ||
| FT | Aberdeen | 2-2 (0-2) | Dundee United |
| FT | CS Fola Esch | 0-3 (0-3) | Racing FC Union Luxembourg | ||
| FT | F91 Dudelange | 3-1 (0-1) | FC Wiltz 71 | ||
| FT | FC Mondercange | 1-0 (1-0) | AS Jeunesse Esch | ||
| FT | Swift Hesperange | 1-0 (1-0) | SC Bettembourg | ||
| FT | US Hostert | 2-2 (2-1) | Una Strassen | ||
| FT | US Mondorf les Bains | 1-1 (0-1) | FC Rodange 91 | ||
| FT | Union Titus Petange | 0-0 (0-0) | FC Victoria Rosport |
| FT | SP Libertas | 2-4 (0-1) | Faetano | ||
| FT | San Giovanni | 2-2 (0-0) | SS Pennarossa | ||
| FT | San Marino Academy U22 | 1-2 (1-1) | Juvenes/Dogana |
| FT | Drita | 2-0 (0-0) | Ferizaj | ||
| FT | Malisheva | 3-1 (1-1) | Ballkani |
| FT | FC Kuressaare | 1-2 (0-0) | Paide Linnameeskond | ||
| FT | Tallinna Kalev | 1-2 (0-1) | Tammeka |
| FT | Elversberg | 4-0 (4-0) | Hertha Berlin | ||
| FT | Magdeburg | 4-1 (0-1) | Darmstadt | ||
| FT | Paderborn | 2-0 (1-0) | Hamburger SV |
| FT | Chengdu Rongcheng FC | 1-2 (1-1) | Tianjin Jinmen Tiger |
| FT | Albirex Niigata | 2-2 (1-1) | Cerezo Osaka | ||
| FT | Fagiano Okayama FC | 1-1 (0-0) | Shimizu S-Pulse | ||
| FT | Nagoya Grampus | 1-2 (1-1) | Machida Zelvia | ||
| FT | Tokyo Verdy | 0-1 (0-0) | Gamba Osaka | ||
| FT | Sanfrecce Hiroshima | 1-0 (0-0) | Yokohama FC | ||
| FT | Urawa Red Diamonds | 0-2 (0-2) | Kashiwa Reysol |
| FT | Western Sydney Wanderers FC | 4-1 (2-1) | Perth Glory |
