| FT | Necaxa | 3-2 (2-2) | Santos Laguna | ||
| FT | Queretaro FC | 1-0 (1-0) | Atletico de San Luis | ||
| FT | Puebla | 1-2 (0-2) | CF America |
| FT | Banfield | 1-1 (1-0) | Belgrano | ||
| FT | Central Cordoba de Santiago | 2-0 (1-0) | Newell's Old Boys | ||
| FT | Huracan | 2-0 (1-0) | Tigre | ||
| FT | Independiente Rivadavia | 2-2 (0-0) | Estudiantes | ||
| FT | Union | 0-1 (0-1) | Argentinos Juniors |
| FT | Aguilas Doradas | 0-0 (0-0) | Santa Fe | ||
| FT | Tolima | 3-1 (2-1) | Alianza FC |
| FT | FC Porto | 1-1 (0-1) | Sporting CP |
| FT | Nantes | 0-2 (0-1) | Brest | ||
| FT | Paris St-Germain | 4-1 (1-1) | Monaco |
| FT | Manchester United | 2-1 (0-1) | Leicester City |
| FT | Rayo Vallecano | 1-0 (0-0) | Real Valladolid |
| FT | Ayr United | 0-1 (0-0) | Hibernian |
| FT | Flint Town United | 2-0 (0-0) | Aberystwyth |
| FT | Como | 1-2 (1-1) | Juventus |
| FT | Ballymena United | 2-2 (1-1) | Linfield |
| FT | KV Mechelen | 3-3 (1-1) | La Gantoise |
| FT | Brescia | 0-0 (0-0) | Salernitana |
| FT | Bayern Munich | 3-0 (0-0) | Werder Bremen |
| FT | Sturm Graz | 2-2 (1-1) | Austria Wien |
| FT | Albacete | 2-1 (0-0) | Saragosse |
| FT | Stal Mielec | 2-1 (2-1) | Jagiellonia Bialystok | ||
| FT | Pogon Szczecin | 3-0 (1-0) | Gornik Zabrze |
| FT | MAT Tetouan | 1-1 (0-0) | Union Touarga Sport | ||
| FT | Salmi | 1-1 (1-1) | Chabab Mohammedia |
| FT | Grenoble | 0-0 (0-0) | Red Star | ||
| FT | Laval | 0-1 (0-0) | Annecy FC | ||
| FT | Martigues | 1-2 (0-2) | Troyes | ||
| FT | Paris FC | 3-1 (1-1) | Pau | ||
| FT | Rodez | 0-2 (0-1) | SC Bastia |
| FT | MTK Budapest | 0-2 (0-1) | Debreceni VSC |
| FT | Lommel | 0-2 (0-1) | Club Brugge NXT |
| FT | Benfica B | 0-1 (0-0) | Feirense |
| FT | Botosani | 1-1 (1-1) | Dinamo Bucarest |
| FT | Greuther Fuerth | 2-1 (2-1) | Jahn Regensburg | ||
| FT | Preussen Muenster | 1-2 (1-1) | Hamburger SV |
| FT | Al-Orobah FC | 4-2 (2-1) | Al-Wehda | ||
| FT | Al Nassr FC | 3-0 (1-0) | Al-Fayha | ||
| FT | Al Ahli | 2-0 (1-0) | Al Fateh FC |
| FT | Samsunspor | 2-0 (2-0) | Hatayspor |
| FT | Omonia 29 Maiou | 2-3 (1-0) | Omonia Nicosia |
| FT | Dinamo Zagreb | 3-0 (1-0) | Sibenik |
| FT | AaB | 2-4 (0-2) | LNZ Cherkasy | ||
| FT | FC Nordsjaelland | 5-1 (2-1) | Freiburg II | ||
| FT | FC Rostov | 1-2 (0-1) | Zenit St. Petersburg | ||
| FT | Sarpsborg 08 | 2-1 (2-1) | Moss | ||
| FT | Stroemsgodset | 4-1 (2-1) | Stabaek | ||
| FT | FC Nordsjaelland | 0-1 (0-0) | AIK | ||
| FT | Qingdao West Coast | 1-2 (1-2) | CSKA Moscow | ||
| FT | Kryvbas | 1-5 (0-3) | Randers FC | ||
| FT | Elfsborg | 2-1 (0-0) | Sandefjord | ||
| FT | Haecken | 1-0 (0-0) | Fredrikstad | ||
| FT | Spartak Moscow | 1-0 (1-0) | Dinamo Moscow |
| FT | NK Bravo | 3-1 (2-1) | Primorje | ||
| FT | Nafta | 2-1 (0-1) | Radomlje |
| FT | Arda Kardzhali | 2-2 (1-1) | Spartak Varna |
| FT | Tekstilac Odzaci | 0-1 (0-1) | Cukaricki |
| FT | Ballkani | 1-0 (0-0) | Dukagjini | ||
| FT | Drita | 2-0 (0-0) | Malisheva |
| FT | Adelaide United | 1-0 (0-0) | Melbourne City FC | ||
| FT | Perth Glory | 1-1 (1-0) | Central Coast Mariners |
| FT | Cibao | 1-1 (1-0) | CD Guadalajara | ||
| FT | Cavalry FC | 2-1 (0-1) | Club Universidad Nacional |
| FT | Jamaïque | 1-0 (0-0) | Trinidad etT. |
| Pen. | Bucaramanga | 0-0(0-0) | Atletico Nacional* |
| FT | Blooming | 3-2 (3-1) | El Nacional |
