| FT | Machida Zelvia | 0-0 (0-0) | Avispa Fukuoka | ||
| FT | Albirex Niigata | 2-2 (0-1) | Kawasaki Frontale | ||
| FT | Tokyo Verdy | 1-0 (0-0) | Nagoya Grampus | ||
| FT | Gamba Osaka | 2-1 (0-0) | Vissel Kobe | ||
| FT | Jubilo Iwata | 1-1 (0-0) | Cerezo Osaka | ||
| FT | Kashiwa Reysol | 0-1 (0-1) | Sanfrecce Hiroshima | ||
| FT | Sagan Tosu | 3-0 (0-0) | Kyoto Sanga FC | ||
| FT | Shonan Bellmare | 0-1 (0-0) | FC Tokyo | ||
| FT | Urawa Red Diamonds | 2-2 (0-2) | Kashima Antlers | ||
| FT | Hokkaido Consadole Sapporo | 0-1 (0-0) | Yokohama F.Marinos |
| FT | Columbus Crew | 4-0 (2-0) | Sporting Kansas City | ||
| FT | DC United | 1-4 (1-0) | Houston Dynamo FC | ||
| FT | FC Cincinnati | 1-2 (0-2) | New England Revolution | ||
| FT | New York Red Bulls | 3-0 (1-0) | Toronto FC | ||
| FT | Orlando City | 4-2 (3-0) | Chicago Fire FC | ||
| FT | Philadelphia Union | 0-2 (0-0) | Charlotte FC | ||
| FT | Minnesota United | 0-1 (0-1) | Austin FC | ||
| FT | Nashville SC | 1-0 (1-0) | New York City FC | ||
| FT | St. Louis City | 1-1 (0-0) | Atlanta United | ||
| FT | Colorado Rapids | 4-1 (2-0) | CF Montreal | ||
| FT | Real Salt Lake | 0-1 (0-0) | LA Galaxy | ||
| FT | Los Angeles FC | 6-2 (4-1) | San Jose Earthquakes | ||
| FT | Portland Timbers | 2-0 (2-0) | Vancouver Whitecaps | ||
| FT | Seattle Sounders FC | 3-2 (0-0) | FC Dallas |
| FT | Equateur | 1-2 (1-0) | Venezuela | ||
| FT | Mexique | 1-0 (0-0) | Jamaïque |
| FT | Criciuma | 2-1 (1-0) | Botafogo RJ | ||
| FT | Gremio | 0-1 (0-0) | Internacional | ||
| FT | Cuiaba | 0-0 (0-0) | Atletico GO | ||
| FT | Vasco da Gama | 4-1 (2-1) | Sao Paulo |
| FT | Vestri | 1-5 (1-1) | Valur | ||
| FT | HK Kopavogs | 4-3 (2-1) | Stjarnan | ||
| FT | Vikingur Reykjavik | 1-1 (1-1) | KR Reykjavik |
| FT | Belgique | 2-0 (1-0) | Roumanie |
| FT | Naftan Novopolotsk | 0-1 (0-0) | Slavia Mozyr | ||
| FT | FC Minsk | 1-2 (0-2) | Arsenal Dzerzhinsk | ||
| FT | BATE Borisov | 3-1 (3-0) | Dynamo Brest |
| FT | AGF | 0-0 (0-0) | Brabrand | ||
| FT | FC Zürich | 5-4 (3-1) | Wil | ||
| FT | FC Kreuzlingen | 0-9 (0-3) | Saint-Gall | ||
| FT | Brechin City | 0-2 (0-1) | Dundee United | ||
| FT | Altach | 3-0 (1-0) | FC Nenzing | ||
| FT | Lausanne | 3-2 (0-2) | FC Stade Lausanne-Ouchy | ||
| FT | KSV Oudenaarde | 0-3 (0-1) | FCV Dender EH | ||
| FT | KVV Zepperen-Brustem | 0-2 (0-1) | St.Truiden |
| FT | FK TransINVEST | 3-0 (2-0) | Dziugas Telsiai | ||
| FT | FK Panevezys | 2-0 (2-0) | Dainava Alytus |
| FT | Géorgie | 1-1 (1-0) | Rép. Tchèque | ||
| FT | Turquie | 0-3 (0-2) | Portugal |
| FT | Jiangxi Lushan | 0-3 (0-1) | Zhejiang Professional | ||
| FT | Chongqing Tongliang Long | 3-6 (0-1) | Shandong Taishan | ||
| FT | Qingdao Red Lions | 0-2 (0-0) | Shenzhen Peng City | ||
| Pen. | Shijiazhuang Gongfu | 2-2(2-2) | Qingdao West Coast* | ||
| FT | Suzhou Dongwu | 0-4 (0-2) | Beijing Guoan |
| FT | Grobina | 0-6 (0-4) | Riga FC |
| FT | Daegu FC | 3-0 (1-0) | Jeonbuk Hyundai Motors FC | ||
| FT | Daejeon Hana Citizen | 2-1 (0-1) | Gwangju FC | ||
| FT | Gangwon FC | 2-3 (2-3) | Gimcheon Sangmu | ||
| FT | FC Seoul | 3-0 (1-0) | Suwon FC |
| FT | Chungnam Asan FC | 4-0 (3-0) | Gyeongnam FC | ||
| FT | FC Anyang | 2-1 (1-1) | Seoul E-Land FC | ||
| FT | Suwon Samsung Bluewings | 3-0 (1-0) | Seongnam FC |
| FT | Pérou | 0-0 (0-0) | Chili |
