| FT | Queretaro FC | 4-1 (2-0) | Atletico de San Luis | ||
| FT | Tigres | 1-0 (0-0) | FC Juarez | ||
| FT | Tijuana | 1-1 (0-0) | Monterrey |
| AP | Philadelphia Union | AP 3-3 | Deportivo Saprissa | ||
| FT | Houston Dynamo FC | 1-0 (0-0) | St. Louis City | ||
| FT | FC Cincinnati | 4-0 (2-0) | Cavalier SC | ||
| FT | Nashville SC | 4-0 (3-0) | Moca FC |
| FT | Marcilio Dias | 1-3 (1-2) | Vasco da Gama | ||
| FT | Olaria | 0-1 (0-0) | Sao Bernardo | ||
| FT | Maringa FC | 2-0 (0-0) | America MG | ||
| FT | Itabuna | 0-8 (0-3) | Nova Iguacu | ||
| FT | Maranhao | 1-2 (1-1) | Ferroviario | ||
| FT | Murici | 2-1 (0-0) | Confianca | ||
| FT | Petrolina SFC | 3-2 (1-0) | FC Cascavel | ||
| FT | ASA | 0-2 (0-1) | Internacional | ||
| FT | Agua Santa | 2-1 (0-1) | EC Jacuipense | ||
| FT | GAS | 0-1 (0-1) | Brusque | ||
| FT | Portuguesa Santista | 0-1 (0-1) | Caxias | ||
| FT | Villa Nova AC | 1-0 (0-0) | Aparecidense | ||
| FT | Humaita SC | 1-1 (0-0) | Sampaio Correa | ||
| FT | Operario MS | 0-0 (0-0) | Operario Ferroviario | ||
| FT | Operario VG | 0-0 (0-0) | Criciuma | ||
| FT | Trem DC | 0-4 (0-2) | Sport Recife |
| Pen. | *Red Bull Bragantino | 0-0(0-0) | Aguilas Doradas | ||
| FT | Sporting Cristal | 3-1 (1-1) | Always Ready | ||
| FT | Nacional | 2-0 (0-0) | Academia Puerto Cabello | ||
| FT | Atletico Nacional | 0-3 (0-1) | Nacional | ||
| FT | Botafogo RJ | 6-0 (3-0) | Aurora |
| FT | San Lorenzo | 1-0 (0-0) | Independiente Chivilcoy |
| FT | Millonarios | 0-2 (0-1) | Once Caldas | ||
| FT | Fortaleza FC | 1-2 (1-2) | Alianza FC |
| FT | Leixoes | 1-1 (0-0) | Nacional |
| FT | Géorgie | 1-0 (1-0) | Macédoine du N. F | ||
| FT | Roumanie F | 0-1 (0-0) | Turquie F | ||
| FT | Danemark F | 1-1 (0-1) | Autriche F | ||
| FT | Bolivie F | 0-1 (0-0) | Pérou F |
| Pen. | Rouen | 1-1(1-1) | Valenciennes* |
| FT | Chelsea | 3-2 (2-1) | Leeds United | ||
| FT | Nottingham | 0-1 (0-0) | Manchester United | ||
| FT | Wolverhampton Wanderers | 1-0 (1-0) | Brighton & Hove Albion | ||
| FT | Liverpool | 3-0 (1-0) | Southampton |
| FT | Aberdeen | 0-2 (0-1) | St. Johnstone | ||
| FT | Celtic | 7-1 (6-0) | Dundee FC | ||
| FT | Hearts | 1-1 (1-1) | Hibernian | ||
| FT | Kilmarnock | 1-2 (1-0) | Rangers | ||
| FT | Livingston | 1-3 (1-0) | Motherwell |
| FT | Sassuolo | 1-6 (1-3) | Naples | ||
| FT | Inter Milan | 4-0 (2-0) | Atalanta |
| FT | Union St.Gilloise | 2-0 (0-0) | Club Brugge |
| FT | Delemont | 0-2 (0-0) | Servette | ||
| Pen. | FC Bâle | 2-2(2-2) | Lugano* | ||
| FT | FC Zürich | 0-2 (0-0) | Winterthur |
| FT | Pisa | 2-2 (1-0) | Modena | ||
| FT | Spezia | 0-2 (0-1) | FeralpiSalo | ||
| FT | Venezia | 2-0 (1-0) | Cittadella |
| FT | Asteras Tripolis | 3-3 (3-2) | Kifisia FC | ||
| FT | NFC Volos | 3-1 (1-1) | OFI Crete | ||
| FT | Atromitos | 3-1 (1-1) | Lamia | ||
| FT | Panetolikos | 1-2 (1-0) | Olympiacos | ||
| FT | AEK Athens | 4-2 (1-2) | PAS Giannina | ||
| FT | Panserraikos FC | 0-2 (0-1) | PAOK Thessaloniki FC | ||
| FT | Panathinaikos | 2-0 (1-0) | Aris Thessaloniki FC |
| FT | Universitatea Cluj | 1-0 (1-0) | FCV Farul Constanta | ||
| FT | Rapid Bucuresti | 4-1 (2-1) | UTA Arad |
| Pen. | Mezoors | 1-1(1-1) | Vasas Budapest* | ||
| FT | Kozarmisleny | 0-3 (0-2) | MTK Budapest | ||
| FT | Veszprem FC | 0-2 (0-0) | Kecskemeti TE | ||
| FT | Tiszakecske | 0-3 (0-0) | Kisvarda | ||
| Pen. | Debreceni VSC | 1-1(1-1) | Ferencvarosi TC* |
| FT | Stal Mielec | 1-0 (1-0) | LKS Lodz |
| FT | Stroemsgodset | 1-0 (1-0) | Lillestroem |
| FT | FK Qabala | 0-4 (0-0) | Qarabag FK |
