| FT | Mazatlan FC | 2-4 (0-2) | Puebla |
| FT | Central Cordoba de Santiago | 1-2 (0-0) | Argentinos Juniors | ||
| FT | Boca Juniors | 0-3 (0-3) | Banfield |
| FT | Guairena | 1-1 (1-1) | Nacional | ||
| FT | Sol de America | 0-1 (0-0) | Sportivo Ameliano |
| FT | Everton CD | 1-1 (1-1) | Colo Colo |
| FT | KR Reykjavik | 0-3 (0-1) | Vikingur Reykjavik |
| FT | Italie F | 1-1 (0-0) | Espagne F | ||
| FT | France F | 7-0 (6-0) | Vietnam F |
| FT | Bohemian FC | 2-3 (0-1) | Derry City | ||
| FT | Dundalk | 3-0 (0-0) | UCD | ||
| FT | St. Patrick's Athletic | 3-0 (1-0) | Drogheda United | ||
| FT | Finn Harps | 0-1 (0-1) | Shamrock Rovers |
| FT | Bray Wanderers | 1-3 (0-2) | Cork City | ||
| FT | Cobh Ramblers | 0-2 (0-1) | Treaty United | ||
| FT | Galway United FC | 1-0 (0-0) | Waterford FC | ||
| FT | Wexford FC | 3-1 (1-0) | Athlone Town |
| FT | Charlton Athletic | 0-1 (0-0) | Kilmarnock | ||
| FT | Hibernian | 4-2 (1-1) | Burton Albion | ||
| FT | Randers FC | 3-2 (0-0) | Viborg | ||
| FT | Burnley | 1-0 (1-0) | Rochdale | ||
| FT | St. Pauli | 0-2 (0-0) | Silkeborg | ||
| FT | Yverdon | 2-0 (0-0) | Grasshopper Zurich | ||
| FT | Amiens | 1-4 (1-1) | Oostende | ||
| FT | Istanbul Basaksehir | 3-0 (1-0) | Metalist Kharkiv | ||
| FT | Ried | 1-1 (0-1) | 1860 Munich | ||
| FT | Young Boys | 2-2 (1-1) | FC Stade Lausanne-Ouchy | ||
| FT | Augsburg | 5-0 (3-0) | VfB Eichstaett | ||
| FT | FC Koeln | 12-1 (3-1) | TuS Mondorf | ||
| FT | La Gantoise | 3-0 (2-0) | Hajduk Split | ||
| FT | Meppen | 2-2 (0-1) | Cambuur | ||
| Pen. | Nizhny Novgorod | 1-1(1-1) | PFC Sochi* | ||
| FT | RW Essen | 2-4 (1-3) | Borussia Moenchengladbach | ||
| FT | Dereham Town | 0-4 (0-2) | Norwich City | ||
| FT | Haringey Borough | 1-2 (0-1) | Leyton Orient | ||
| FT | Hitchin Town | 0-3 (0-2) | Luton Town | ||
| FT | Melksham Town | 1-6 (0-3) | Bristol Rovers | ||
| FT | Parkgate FC | 2-4 (0-2) | Rotherham United | ||
| FT | Penrith AFC | 1-5 (0-1) | Carlisle United | ||
| FT | Undy Athletic | 0-7 (0-3) | Newport County | ||
| FT | Tiverton | 2-1 (0-0) | Exeter City | ||
| FT | Bradford PA | 0-2 (0-1) | Bradford City |
| FT | GIF Sundsvall | 2-1 (2-1) | Malmoe FF |
| FT | Zalgiris Vilnius | 2-1 (1-0) | Hegelmann |
| FT | FK Liepaja | 0-0 (0-0) | Riga FC |
| FT | FCI Levadia | 3-1 (2-0) | Talinna Kalev |
| FT | Jiangxi Lushan | 3-1 (2-0) | Beijing Technology | ||
| FT | Kunshan FC | 3-1 (2-1) | Nanjing City FC | ||
| FT | Shenzhen Peng City | 3-0 (3-0) | Liaoning Tieren | ||
| FT | Dingnan United | 3-1 (1-1) | Xinjiang Tianshan |
| FT | Fortaleza | 1-1 (0-0) | Estudiantes |
| FT | Olimpia | 2-0 (1-0) | Atletico GO | ||
| FT | Universidad Catolica | 2-4 (0-3) | Sao Paulo |
| FT | New York Red Bulls | 2-1 (0-0) | Atlanta United |
