| FT | Gangwon FC | 0-0 (0-0) | Suwon FC | ||
| FT | Incheon United | 2-1 (0-1) | Gwangju FC | ||
| FT | Jeju SK | 1-2 (0-1) | Daegu FC |
| FT | New York City FC | 1-1 (0-0) | Toronto FC | ||
| FT | LA Galaxy | 2-0 (1-0) | Austin FC | ||
| FT | Atlanta United | 1-0 (0-0) | CF Montreal | ||
| FT | Philadelphia Union | 1-0 (1-0) | New York Red Bulls | ||
| FT | Minnesota United | 1-0 (0-0) | FC Dallas | ||
| FT | Colorado Rapids | 3-1 (3-1) | Houston Dynamo FC | ||
| FT | Real Salt Lake | 0-0 (0-0) | Nashville SC | ||
| FT | San Jose Earthquakes | 0-2 (0-1) | Portland Timbers |
| FT | Puebla | 1-0 (0-0) | Atlas | ||
| FT | Cruz Azul | 3-1 (1-1) | Toluca |
| Pen. | Estudiantes | 0-0(0-0) | Independiente* | ||
| Pen. | *Colon | 1-1(1-1) | Talleres |
| FT | Sol de America | 0-2 (0-1) | Luqueno | ||
| FT | 12 de Octubre | 1-1 (0-1) | Guairena |
| FT | Deportivo Cuenca | 1-2 (0-1) | Mushuc Runa | ||
| FT | Olmedo | 1-3 (1-0) | Independiente del Valle | ||
| FT | Universidad Catolica | 0-1 (0-0) | Delfin | ||
| FT | Emelec | 1-0 (0-0) | Guayaquil City |
| FT | Boavista | 1-0 (0-0) | Portimonense | ||
| FT | Farense | 1-0 (0-0) | Tondela | ||
| FT | Benfica | 4-3 (3-1) | Sporting CP | ||
| FT | Rio Ave | 0-3 (0-0) | FC Porto |
| FT | Olympic Club de Safi | 1-1 (0-0) | Ittihad Tanger | ||
| FT | Renaissance Club Zemamra | 1-1 (0-0) | Chabab Mohammedia | ||
| FT | MAT Tetouan | 0-0 (0-0) | FAR Rabat |
| FT | NAC Breda | 4-1 (1-0) | FC Volendam | ||
| FT | De Graafschap | 2-3 (2-1) | Roda JC Kerkrade | ||
| FT | Almere City FC | 0-4 (0-2) | NEC Nijmegen |
| FT | CR Belouizdad | 2-0 (1-0) | Esperance | ||
| FT | Kaizer Chiefs | 4-0 (2-0) | Simba SC | ||
| FT | Al Ahly SC | 2-0 (1-0) | Mamelodi Sundowns FC |
| FT | Castellon | 0-2 (0-1) | Ponferradina | ||
| FT | Lugo | 2-1 (0-1) | CD Mirandes | ||
| FT | Almeria | 1-1 (1-1) | Albacete | ||
| FT | Las Palmas | 0-2 (0-1) | Saragosse |
| FT | Burnley | 0-4 (0-1) | Leeds United | ||
| FT | Southampton | 3-1 (1-0) | Fulham | ||
| FT | Brighton & Hove Albion | 1-1 (0-0) | West Ham United |
| FT | Dundee FC | 0-1 (0-1) | Raith Rovers |
| FT | Anderlecht | 1-2 (1-1) | RC Genk |
| FT | Genoa | 3-4 (0-3) | Atalanta | ||
| FT | Spezia | 4-1 (2-0) | Torino | ||
| FT | Juventus | 3-2 (2-1) | Inter Milan | ||
| FT | Roma | 2-0 (1-0) | Lazio |
| FT | Universitatea Craiova | 1-3 (1-1) | CFR 1907 Cluj |
| FT | FC Bâle | 4-0 (2-0) | FC Zürich | ||
| FT | FC Vaduz | 1-3 (1-1) | Servette | ||
| FT | Lugano | 3-1 (2-1) | Sion | ||
| FT | Saint-Gall | 5-0 (3-0) | Lausanne | ||
| FT | Young Boys | 5-2 (1-2) | FC Lucerne |
| FT | Cobh Ramblers | 1-2 (1-0) | Shelbourne |
| FT | Al Fateh FC | 2-3 (2-2) | Al-Wehda | ||
| FT | Al-Raed | 1-2 (0-1) | Al-Taawoun | ||
| FT | Damac FC | 1-1 (1-0) | Al Ittihad |
| FT | NK Bravo | 1-1 (1-1) | Tabor | ||
| FT | Maribor | 3-0 (2-0) | Gorica | ||
| FT | Aluminij | 0-0 (0-0) | Mura |
| FT | Caen | 2-1 (0-0) | Clermont Foot | ||
| FT | Châteauroux | 0-0 (0-0) | AC Ajaccio | ||
| FT | Dunkerque | 3-3 (1-1) | Toulouse | ||
| FT | Grenoble | 1-0 (0-0) | Rodez | ||
| FT | Le Havre | 3-2 (2-1) | Troyes | ||
| FT | Nancy | 2-2 (0-1) | Amiens | ||
| FT | Niort | 0-2 (0-1) | Guingamp | ||
| FT | Paris FC | 3-0 (0-0) | Chambly | ||
| FT | Pau | 4-3 (3-0) | Valenciennes | ||
| FT | Sochaux | 2-3 (1-0) | Auxerre |
| FT | Neman Grodno | 1-2 (1-1) | Shakhtyor Soligorsk | ||
| FT | FK Vitebsk | 3-2 (0-2) | Energetik-BGU | ||
| FT | Torpedo Zhodino | 3-3 (1-2) | Isloch | ||
| FT | BATE Borisov | 3-2 (1-2) | Rukh Brest |
| FT | Ankaragucu | 0-1 (0-1) | Alanyaspor | ||
| FT | Antalyaspor | 0-0 (0-0) | Konyaspor | ||
| FT | Fatih Karagumruk | 5-1 (2-1) | Denizlispor | ||
| FT | Hatayspor | 0-1 (0-0) | Gaziantep FK | ||
| FT | Sivasspor | 2-1 (1-0) | Kasimpasa | ||
| FT | Çaykur Rizespor | 0-2 (0-2) | Istanbul Basaksehir | ||
| FT | Galatasaray | 3-1 (0-1) | Yeni Malatyaspor | ||
| FT | Goztepe | 1-2 (1-1) | Besiktas | ||
| FT | Kayserispor | 1-2 (1-0) | Fenerbahce | ||
| FT | Trabzonspor | 2-1 (1-0) | Genclerbirligi |
| FT | Opava | 1-2 (0-1) | Sigma Olomouc | ||
| FT | Banik Ostrava | 4-2 (2-0) | FC Zlin | ||
| FT | Pribram | 1-0 (0-0) | Jablonec | ||
| FT | Slovacko | 1-1 (1-1) | Bohemians 1905 |
| FT | NK Istra 1961 | 1-0 (0-0) | Slaven | ||
| FT | NK Lokomotiva | 0-2 (0-0) | Osijek |
| FT | Ludogorets Razgrad | 4-1 (2-1) | Arda Kardzhali | ||
| FT | Lokomotiv Plovdiv | 2-0 (0-0) | PFK CSKA Sofia |
| FT | Longford Town | 0-2 (0-1) | Bohemian FC | ||
| FT | Shamrock Rovers | 1-1 (0-0) | Derry City | ||
| Abd. | Sligo Rovers | 3-0 (0-0) | Waterford FC |
| FT | AE Larissa | 2-0 (2-0) | PAS Giannina | ||
| FT | Apollon Smirnis | 0-1 (0-1) | Lamia | ||
| FT | Atromitos | 1-0 (0-0) | NFC Volos | ||
| FT | OFI Crete | 2-2 (1-0) | Panetolikos |
| FT | Chelsea | 0-1 (0-0) | Leicester City |
| FT | Zlate Moravce | 0-4 (0-2) | Slovan Bratislava | ||
| FT | Trencin | 1-1 (0-0) | DAC 1904 Dunajska Streda |
| FT | Altach | 3-0 (1-0) | Ried | ||
| FT | Austria Wien | 2-1 (1-1) | SKN St. Poelten | ||
| FT | Hartberg | 2-0 (1-0) | Admira Wacker |
| FT | FK Senica | 0-0 (0-0) | FK Pohronie | ||
| FT | Ruzomberok | 2-0 (0-0) | Nitra | ||
| FT | Zemplin Michalovce | 2-2 (1-1) | SKF Sered |
| FT | Chaves | 3-1 (1-1) | Leixoes | ||
| FT | AVS Futebol SAD | 0-0 (0-0) | Cova da Piedade | ||
| FT | Mafra | 0-1 (0-1) | Arouca |
| FT | Crusaders | 0-1 (0-0) | Coleraine | ||
| FT | Glentoran | 0-2 (0-0) | Cliftonville | ||
| FT | Linfield | 1-2 (0-0) | Larne |
| FT | Dungannon Swifts | 1-3 (0-1) | Ballymena United | ||
| FT | Portadown | 2-1 (1-0) | Carrick Rangers |
| FT | AC Oulu | 0-2 (0-0) | SJK | ||
| FT | HIFK | 1-1 (1-0) | Ilves |
| FT | FK Metalac | 1-1 (1-0) | Novi Pazar | ||
| FT | Indjija | 0-5 (0-3) | RFK Novi Sad | ||
| FT | Javor | 1-2 (0-0) | Cukaricki | ||
| FT | Napredak | 2-0 (1-0) | Mladost Lucani | ||
| FT | Rad Beograd | 7-1 (4-0) | Macva Sabac | ||
| FT | Zlatibor | 0-0 (0-0) | Radnicki Nis | ||
| FT | Partizan Beograd | 3-0 (1-0) | Vozdovac |
| FT | CSM Politehnica Iasi | 0-1 (0-0) | Hermannstadt | ||
| FT | Astra Giurgiu | 0-3 (0-1) | FC Voluntari |
| FT | Arminia Bielefeld | 1-1 (1-1) | Hoffenheim | ||
| FT | Augsburg | 2-0 (0-0) | Werder Bremen | ||
| FT | Bayer Leverkusen | 1-1 (1-0) | Union Berlin | ||
| FT | Borussia Moenchengladbach | 1-2 (1-0) | VfB Stuttgart | ||
| FT | Freiburg | 2-2 (1-1) | Bayern Munich | ||
| FT | Hertha Berlin | 0-0 (0-0) | FC Koeln | ||
| FT | Schalke 04 | 4-3 (1-1) | Eintracht Frankfurt |
| FT | Parnu JK Vaprus | 0-4 (0-1) | FCI Levadia | ||
| FT | Tulevik Viljandi | 1-2 (0-0) | FC Kuressaare | ||
| FT | Narva Trans | 0-3 (0-0) | TJK Legion |
| FT | Beijing Sports University FC | 0-1 (0-1) | Nanjing City FC | ||
| FT | Beijing Technology | 2-0 (2-0) | Guizhou F.C. | ||
| FT | Kunshan FC | 6-0 (3-0) | Jiangxi Lushan | ||
| FT | Xinjiang Tianshan | 0-2 (0-1) | Zhejiang Professional |
| FT | Hibernian | 0-0 (0-0) | Celtic | ||
| FT | Rangers | 4-0 (2-0) | Aberdeen | ||
| FT | St. Johnstone | 0-0 (0-0) | Livingston |
| FT | Cardiff Met University | 2-1 (1-0) | Flint Town United | ||
| FT | Haverfordwest | 2-0 (1-0) | Cefn Druids AFC | ||
| FT | Newtown | 0-4 (0-1) | Aberystwyth |
| FT | Barry Town | 3-2 (0-1) | Caernarfon | ||
| FT | Penybont | 0-2 (0-1) | Connah's Quay Nomads | ||
| FT | TNS | 2-0 (1-0) | Bala Town |
| FT | Qingdao FC | 1-0 (0-0) | Chongqing Liangjiang Athletic |
| FT | FK Kauno Zalgiris | 1-0 (0-0) | Dziugas Telsiai |
| FT | Western United FC | 0-1 (0-0) | Sydney FC | ||
| FT | Newcastle Jets | 0-1 (0-0) | Central Coast Mariners |
| FT | Shimizu S-Pulse | 0-3 (0-1) | Nagoya Grampus | ||
| FT | Vegalta Sendai | 0-1 (0-0) | Avispa Fukuoka | ||
| FT | Kashima Antlers | 5-3 (1-1) | Yokohama F.Marinos | ||
| FT | Kashiwa Reysol | 0-4 (0-3) | FC Tokyo | ||
| FT | Oita Trinita | 1-1 (0-1) | Sagan Tosu | ||
| FT | Sanfrecce Hiroshima | 0-1 (0-0) | Tokushima Vortis | ||
| FT | Vissel Kobe | 1-1 (0-0) | Cerezo Osaka | ||
| FT | Yokohama FC | 2-0 (1-0) | Shonan Bellmare |
| FT | Gimcheon Sangmu | 1-1 (0-1) | Daejeon Hana Citizen |
