| FT | Universidad Catolica | 0-0 (0-0) | Colo Colo | ||
| FT | Palestino | 1-0 (1-0) | Audax Italiano | ||
| FT | Antofagasta | 1-1 (1-1) | Santiago Wanderers | ||
| FT | Universidad de Chile | 2-2 (2-2) | Huachipato | ||
| FT | Coquimbo Unido | 0-3 (0-2) | O'Higgins |
| FT | Independiente | 1-2 (1-0) | Boca Juniors | ||
| FT | Huracan | 1-3 (0-2) | River Plate |
| FT | LDU Portoviejo | 3-2 (1-1) | Aucas | ||
| FT | Orense | 1-0 (0-0) | El Nacional | ||
| FT | CSD Macara | 1-0 (1-0) | Independiente del Valle | ||
| FT | Emelec | 4-1 (4-1) | Olmedo | ||
| FT | LDU de Quito | 1-2 (1-2) | Tecnico Universitario | ||
| FT | Universidad Catolica | 0-0 (0-0) | Barcelona SC |
| FT | Sport Recife | 1-1 (1-0) | Gremio | ||
| FT | Coritiba | 1-2 (1-0) | Botafogo RJ | ||
| FT | Internacional | 2-0 (1-0) | Palmeiras | ||
| FT | Red Bull Bragantino | 0-1 (0-1) | Athletico Paranaense | ||
| FT | Vasco da Gama | 1-0 (1-0) | Santos FC | ||
| FT | Flamengo | 4-3 (2-0) | Bahia | ||
| FT | Fortaleza | 0-2 (0-0) | Ceara |
| FT | America de Cali | 3-0 (1-0) | Santa Fe |
| FT | Godoy Cruz | 0-3 (0-2) | Newell's Old Boys | ||
| FT | Estudiantes | 1-1 (0-1) | Racing Club |
| FT | Lanus | 1-1 (1-1) | Defensa y Justicia |
| FT | Celta Vigo | 2-0 (1-0) | Deportivo Alaves | ||
| FT | Granada CF | 2-0 (2-0) | Real Betis | ||
| FT | Cadiz | 0-2 (0-1) | Getafe | ||
| FT | Eibar | 1-3 (1-2) | Real Madrid |
| FT | Pacos de Ferreira | 1-1 (0-0) | Boavista | ||
| FT | Gil Vicente | 0-2 (0-0) | Benfica | ||
| FT | FC Porto | 2-0 (2-0) | Nacional |
| FT | Brest | 2-2 (0-1) | Montpellier | ||
| FT | Dijon | 0-1 (0-1) | Monaco | ||
| FT | Nantes | 1-1 (0-1) | Angers | ||
| FT | St-Etienne | 2-2 (1-1) | Nîmes | ||
| FT | Strasbourg | 0-2 (0-1) | Bordeaux | ||
| FT | Lorient | 0-3 (0-1) | Rennes | ||
| FT | Lille | 0-0 (0-0) | Paris St-Germain |
| FT | Torino | 1-1 (0-0) | Bologna | ||
| FT | Benevento | 2-0 (0-0) | Genoa | ||
| FT | Cagliari | 1-1 (1-0) | Udinese | ||
| FT | Inter Milan | 2-1 (0-0) | Spezia | ||
| FT | Sassuolo | 1-2 (0-2) | AC Milan | ||
| FT | Atalanta | 4-1 (0-1) | Roma | ||
| FT | Lazio | 2-0 (1-0) | Naples |
| FT | Club Brugge | 0-1 (0-0) | La Gantoise | ||
| FT | OH Leuven | 1-2 (0-2) | KV Mechelen | ||
| FT | Standard Liege | 0-1 (0-1) | Royal Excel Mouscron | ||
| FT | SK Beveren | 0-3 (0-3) | Royal Antwerp |
| Pen. | St Pierroise JS | 4-5(4-5) | FC Mtsapere | ||
| FT | US Sinnamary | 2-0 (0-0) | Phare du Canal |
| FT | Alcorcon | 2-1 (2-0) | Cartagena | ||
| FT | Espanyol | 2-1 (1-0) | Almeria | ||
| FT | Rayo Vallecano | 2-0 (0-0) | Las Palmas | ||
| FT | Malaga | 0-0 (0-0) | Logrones |
| FT | Brighton & Hove Albion | 1-1 (0-0) | Sheffield United | ||
| FT | Tottenham Hotspur | 0-2 (0-1) | Leicester City | ||
| FT | Manchester United | 6-2 (4-1) | Leeds United | ||
| FT | West Bromwich Albion | 0-3 (0-1) | Aston Villa |
| FT | Hermannstadt | 0-1 (0-0) | CSM Politehnica Iasi | ||
| FT | Botosani | 1-1 (0-0) | FC Voluntari | ||
| FT | FC Academica Clinceni | 1-1 (0-0) | Dinamo Bucarest |
| FT | Lyngby | 0-0 (0-0) | Vejle Boldklub | ||
| FT | Soenderjyske Fodbold | 0-1 (0-0) | Randers FC | ||
| FT | AGF | 3-0 (3-0) | AaB | ||
| FT | FC Koebenhavn | 1-1 (1-0) | OB | ||
| FT | AC Horsens | 1-2 (0-1) | Broendby IF |
| FT | Union St.Gilloise | 2-1 (1-1) | Westerlo | ||
| FT | Deinze | 0-0 (0-0) | RFC Seraing |
| FT | FAR Rabat | 0-0 (0-0) | FUS Rabat | ||
| FT | MCO Oujda | 1-2 (1-1) | Renaissance Club Zemamra | ||
| FT | Difaa El Jadida | 1-2 (1-2) | MAS Fes | ||
| FT | Ittihad Tanger | 1-1 (1-1) | MAT Tetouan |
| FT | Hapoel Ironi Kiryat Shmona | 0-1 (0-0) | Bnei Sakhnin | ||
| FT | Hapoel Tel Aviv | 0-3 (0-1) | Hapoel Beer Sheva |
| FT | Olympiacos | 5-1 (2-1) | AE Larissa | ||
| FT | PAOK Thessaloniki FC | 2-1 (1-1) | Panathinaikos |
| FT | Pardubice | 0-0 (0-0) | FC Zlin | ||
| FT | Teplice | 1-0 (0-0) | FC Zbrojovka Brno | ||
| FT | Slovacko | 4-0 (1-0) | Viktoria Plzen | ||
| FT | Slavia Prague | 2-1 (1-0) | Bohemians 1905 |
| FT | Freiburg | 4-1 (1-0) | Hertha Berlin | ||
| FT | VFL Wolfsburg | 1-0 (0-0) | VfB Stuttgart |
| FT | Piast Gliwice | 0-0 (0-0) | Rakow Czestochowa | ||
| FT | Jagiellonia Bialystok | 1-0 (0-0) | Gornik Zabrze |
| FT | Hibernians | 2-1 (0-0) | Balzan FC | ||
| FT | Santa Lucia F.C. | 3-2 (2-1) | Gudja United |
| FT | Domzale | 0-0 (0-0) | NK Bravo | ||
| FT | NK Celje | 1-3 (0-1) | Mura | ||
| FT | Maribor | 2-2 (2-2) | Aluminij |
| FT | Hajduk Split | 2-4 (1-1) | HNK Gorica |
| FT | Mafra | 2-2 (0-0) | Oliveirense | ||
| FT | Academica | 1-1 (0-0) | Casa Pia AC | ||
| FT | Benfica B | 1-1 (1-1) | Vizela | ||
| FT | Arouca | 1-0 (0-0) | Sporting Covilha |
| FT | Genclerbirligi | 1-1 (0-0) | Ankaragucu | ||
| FT | Denizlispor | 1-0 (1-0) | Alanyaspor | ||
| FT | Besiktas | 4-0 (0-0) | Erzurumspor FK |
| FT | Red Bull Salzbourg | 2-3 (0-0) | Wolfsberger AC | ||
| FT | WSG Tirol | 1-3 (1-0) | Ried | ||
| FT | Austria Wien | 1-1 (1-1) | LASK |
| FT | Mezokovesd SE | 1-0 (1-0) | Puskas FC Academy | ||
| FT | Ujpest | 2-1 (0-0) | Budapest Honved |
| FT | Apollon Limassol | 4-0 (2-0) | Ermis Aradippou | ||
| FT | Ethnikos Achnas | 0-1 (0-1) | Doxa Katokopia |
| FT | Vitesse Arnhem | 1-0 (1-0) | Feyenoord | ||
| FT | ADO La Haye | 2-4 (0-4) | Ajax Amsterdam | ||
| FT | SC Heerenveen | 1-2 (0-1) | Heracles | ||
| FT | AZ Alkmaar | 5-3 (2-2) | Willem II |
| FT | FC Zürich | 0-1 (0-0) | Servette | ||
| FT | Lausanne | 2-1 (0-1) | FC Lucerne | ||
| FT | Sion | 2-1 (0-0) | FC Vaduz |
| Pen. | *Celtic | 3-3(2-2) | Hearts |
| FT | Javor | 1-2 (0-0) | TSC Backa Topola |
| FT | FK Qabala | 1-1 (0-0) | Qarabag FK | ||
| FT | Shamakhi FK | 0-2 (0-2) | Sabail | ||
| FT | Zira | 2-2 (0-1) | Sumqayit | ||
| FT | Sabah FK | 0-2 (0-1) | FK Neftchi |
| FT | FC Prishtina | 1-1 (1-0) | Drita |
| FT | Nuernberg | 1-0 (1-0) | Erzgebirge Aue | ||
| FT | Sandhausen | 0-2 (0-0) | Holstein Kiel | ||
| FT | St. Pauli | 0-3 (0-1) | Fortuna Duesseldorf |
| FT | Ludogorets Razgrad | 2-1 (1-0) | Botev Plovdiv |
| FT | Kilmarnock | 0-2 (0-0) | Aberdeen |
| FT | Tigres | 3-0 (1-0) | CD Olimpia | ||
| FT | Los Angeles FC | 3-1 (0-1) | CF America |
| FT | San Lorenzo | 2-2 (1-0) | Colon | ||
| FT | Talleres | 1-1 (0-1) | Atletico Tucuman |
| FT | Guarani | 1-0 (0-0) | Guairena | ||
| FT | Libertad | 2-1 (1-1) | Olimpia |
