| FT | CRB | 1-0 (1-0) | Juventude | ||
| FT | America MG | 3-1 (2-0) | Ponte Preta |
| FT | Cucuta | 3-3 (1-2) | Deportivo Cali |
| FT | Binacional | 0-6 (0-3) | River Plate | ||
| FT | LDU de Quito | 4-2 (3-0) | Sao Paulo |
| FT | Barcelona SC | 1-2 (0-2) | Flamengo | ||
| FT | Junior FC | 4-1 (1-1) | Independiente del Valle |
| FT | Estudiantes Merida | 1-3 (1-2) | Nacional |
| FT | Tigre | 1-1 (1-1) | Bolivar |
| FT | Cosmos | 1-6 (1-1) | Tre Fiori |
| Abd. | Leyton Orient | 0-0 (0-0) | Tottenham Hotspur | ||
| FT | Newport County | 3-1 (2-0) | Watford | ||
| Pen. | West Bromwich Albion | 2-2(2-2) | Brentford* | ||
| FT | West Ham United | 5-1 (2-0) | Hull City | ||
| FT | Luton Town | 0-3 (0-1) | Manchester United |
| FT | FC Krasnodar | 2-1 (1-1) | PAOK Thessaloniki FC | ||
| FT | Maccabi Tel Aviv | 1-2 (1-0) | Red Bull Salzbourg | ||
| FT | Slavia Prague | 0-0 (0-0) | FC Midtjylland |
| FT | Feirense | 2-1 (0-1) | Casa Pia AC | ||
| FT | Vizela | 2-1 (0-1) | Sporting Covilha | ||
| FT | Varzim | 0-0 (0-0) | Arouca |
| FT | Kazakhstan | 0-5 (0-1) | Autriche F | ||
| FT | Macédoine du N. F | 0-7 (0-3) | France F |
| FT | Drogheda United | 3-2 (1-1) | Shamrock Rovers II |
| FT | Sudtirol | 2-1 (2-0) | Latte Dolce | ||
| FT | Ternana | 1-2 (0-2) | AlbinoLeffe |
| FT | Lettonie F | 0-5 (0-3) | Hongrie F | ||
| FT | Islande F | 1-1 (0-1) | Suède F |
| FT | SKF Sered | 1-1 (0-1) | Trencin |
| FT | Roumanie F | 4-1 (3-1) | Croatie F | ||
| FT | Suisse F | 2-1 (1-0) | Belgique F |
| FT | Bosnie Herz. F | 0-5 (0-2) | Italie F | ||
| FT | Malte F | 0-8 (0-3) | Danemark F |
| FT | Monténegro F | 0-3 (0-2) | Allemagne F | ||
| FT | Ukraine F | 4-0 (0-0) | Grèce F |
| FT | Pologne F | 0-2 (0-1) | Rép. Tchèque F |
| FT | Norvège F | 1-0 (1-0) | Pays de Galles F | ||
| FT | Îles Féroé F | 0-2 (0-0) | Biélorussie F |
| FT | Arberia | 1-1 (1-1) | FC Prishtina | ||
| FT | Drenica | 2-1 (1-1) | Besa Peje |
| FT | Estonie F | 0-3 (0-1) | Russie F |
| FT | Beijing Guoan | 5-1 (3-0) | Qingdao FC | ||
| FT | Tianjin Jinmen Tiger | 0-1 (0-0) | Hebei FC | ||
| FT | Chongqing Liangjiang Athletic | 1-0 (1-0) | Wuhan Yangtze River | ||
| FT | Cangzhou Mighty Lions F.C. | 0-1 (0-0) | Shanghai Port |
| FT | Leon | 2-0 (1-0) | Club Universidad Nacional |
