| FT | Alianza FC | 0-1 (0-1) | Tolima | ||
| FT | Deportivo Pasto | 1-2 (0-0) | Internacional de Bogota | ||
| FT | Aguilas Doradas | 1-1 (0-0) | Envigado | ||
| FT | Cucuta | 0-1 (0-0) | Bucaramanga | ||
| FT | Deportivo Pereira | 1-3 (1-2) | Once Caldas |
| FT | Central Cordoba de Santiago | 1-1 (0-1) | Banfield | ||
| FT | Godoy Cruz | 1-3 (1-1) | Union | ||
| FT | Aldosivi | 1-3 (0-1) | San Lorenzo | ||
| FT | Lanus | 1-1 (0-0) | Estudiantes | ||
| FT | Rosario Central | 3-1 (1-0) | Arsenal Sarandi | ||
| FT | Velez Sarsfield | 2-0 (1-0) | Argentinos Juniors |
| FT | CF America | 0-3 (0-2) | Necaxa | ||
| FT | Tigres | 3-0 (1-0) | Club Universidad Nacional | ||
| FT | CD Guadalajara | 2-0 (0-0) | Leon | ||
| FT | Santos Laguna | 1-0 (1-0) | Atlas |
| FT | Nashville SC | 1-2 (1-2) | Atlanta United | ||
| FT | Vancouver Whitecaps | 1-3 (1-2) | Sporting Kansas City | ||
| FT | Columbus Crew | 1-0 (0-0) | New York City FC | ||
| FT | New York Red Bulls | 3-2 (2-0) | FC Cincinnati | ||
| FT | Seattle Sounders FC | 2-1 (0-0) | Chicago Fire FC | ||
| FT | Los Angeles FC | 1-0 (1-0) | Inter Miami CF | ||
| FT | Portland Timbers | 1-3 (0-0) | Minnesota United |
| FT | Coquimbo Unido | 2-1 (1-0) | La Serena | ||
| FT | O'Higgins | 2-3 (2-1) | Universidad de Chile | ||
| FT | Palestino | 2-2 (0-2) | Antofagasta |
| FT | Cerro Porteno | 0-1 (0-0) | General Diaz | ||
| FT | Luqueno | 0-3 (0-0) | Guarani |
| FT | Barcelona SC | 1-1 (0-0) | LDU Portoviejo | ||
| FT | Independiente del Valle | 1-2 (0-0) | Olmedo | ||
| FT | Aucas | 3-0 (1-0) | Mushuc Runa | ||
| FT | CSD Macara | 1-0 (1-0) | Emelec |
| FT | Pescara | 2-1 (1-1) | Ascoli Calcio 1898 FC |
| FT | Aves | 1-3 (1-1) | Pacos de Ferreira | ||
| FT | Maritimo | 1-2 (0-1) | Braga | ||
| FT | Vitoria de Guimaraes | 2-0 (2-0) | Tondela |
| FT | FC Séville | 3-2 (2-0) | Osasuna | ||
| FT | Athletic Bilbao | 1-0 (0-0) | Villarreal | ||
| FT | Espanyol | 1-1 (1-0) | Atletico Madrid | ||
| FT | Mallorca | 0-1 (0-0) | Getafe | ||
| FT | Real Madrid | 2-0 (0-0) | Barcelona |
| FT | Nantes | 0-1 (0-0) | Lille | ||
| FT | Bordeaux | 1-1 (1-0) | Nice | ||
| FT | Lyon | 2-0 (1-0) | St-Etienne |
| FT | Enyimba | 1-1 (1-0) | Horoya AC | ||
| FT | Zanaco | 0-3 (0-2) | Pyramids FC | ||
| FT | Al-Nasr | 0-5 (0-2) | Hassania Agadir | ||
| FT | Al Masry SC | 2-2 (0-1) | RSB Berkane |
| FT | RC Genk | 1-2 (1-1) | Club Brugge | ||
| FT | Sporting Charleroi | 2-0 (1-0) | Standard Liege | ||
| FT | Cercle Bruges | 1-0 (1-0) | La Gantoise |
| FT | RKC Waalwijk | 2-1 (0-1) | FC Utrecht | ||
| FT | PSV Eindhoven | 1-1 (0-1) | Feyenoord | ||
| FT | Sparta Rotterdam | 5-1 (3-0) | FC Emmen | ||
| FT | Ajax Amsterdam | 0-2 (0-1) | AZ Alkmaar |
| FT | Sektzia Nes Tziona | 1-0 (0-0) | Hapoel Ironi Kiryat Shmona | ||
| FT | Beitar Jerusalem | 2-1 (1-0) | FC Ashdod | ||
| FT | Maccabi Haifa | 4-0 (2-0) | Hapoel Beer Sheva |
| FT | Universitatea Craiova | 2-1 (2-1) | Gaz Metan Medias |
| FT | CD Mirandes | 1-1 (0-0) | Girona | ||
| FT | Deportivo La Coruna | 0-0 (0-0) | Lugo | ||
| FT | Elche | 2-0 (1-0) | Numancia | ||
| FT | Fuenlabrada | 3-4 (1-3) | Alcorcon | ||
| FT | Real Oviedo | 1-0 (0-0) | Tenerife |
| FT | Tromsoe | 1-1 (0-0) | Viking |
| FT | Renaissance Club Zemamra | 1-2 (1-0) | MAT Tetouan | ||
| FT | Raja Beni Mellal | 0-0 (0-0) | Olympic Club de Safi |
| FT | Lecce | 2-7 (2-2) | Atalanta | ||
| FT | Cagliari | 3-4 (1-2) | Roma |
| FT | AE Larissa | 3-0 (3-0) | Asteras Tripolis | ||
| FT | Aris Thessaloniki FC | 1-2 (0-0) | Atromitos | ||
| FT | OFI Crete | 3-0 (3-0) | Lamia | ||
| FT | Olympiacos | 2-0 (0-0) | Panetolikos | ||
| FT | Panathinaikos | 4-1 (2-0) | NFC Volos | ||
| FT | Panionios | 1-1 (1-0) | AEK Athens | ||
| FT | Xanthi | 1-1 (1-1) | PAOK Thessaloniki FC |
| FT | Vozdovac | 1-2 (1-1) | Vojvodina | ||
| FT | FK Radnik Surdulica | 1-0 (1-0) | Rad Beograd | ||
| FT | Javor | 2-2 (1-1) | FK Spartak Subotica | ||
| FT | Mladost Lucani | 1-0 (0-0) | Cukaricki | ||
| FT | RFK Novi Sad | 1-1 (0-0) | Macva Sabac | ||
| FT | Radnicki Nis | 2-1 (0-0) | Indjija | ||
| FT | TSC Backa Topola | 2-1 (1-0) | Napredak | ||
| FT | FK Crvena Zvezda | 0-0 (0-0) | Partizan Beograd |
| FT | AC Horsens | 1-2 (1-1) | Randers FC | ||
| FT | OB | 1-1 (1-0) | Silkeborg | ||
| FT | Broendby IF | 1-0 (0-0) | Lyngby | ||
| FT | FC Koebenhavn | 3-2 (0-0) | AaB |
| FT | Aston Villa | 1-2 (1-2) | Manchester City |
| FT | Korona Kielce | 1-2 (0-1) | Lechia Gdansk | ||
| FT | Arka Gdynia | 1-1 (0-0) | LKS Lodz | ||
| FT | Zaglebie Lubin | 3-1 (0-0) | Slask Wroclaw |
| FT | Iberia 1999 | 2-1 (1-1) | Chikhura | ||
| FT | Torpedo Kutaisi | 0-2 (0-1) | Dila Gori | ||
| FT | Lokomotivi Tbilisi | 3-1 (3-1) | Samtredia |
| FT | Anorthosis | 1-2 (0-1) | AEK Larnaca | ||
| FT | Enosis Paralimni | 3-0 (0-0) | Olympiakos Nicosia |
| FT | Denizlispor | 2-0 (1-0) | Yeni Malatyaspor | ||
| FT | Ankaragucu | 0-3 (0-0) | Sivasspor | ||
| FT | Galatasaray | 3-0 (2-0) | Genclerbirligi |
| FT | LASK | 5-1 (0-1) | Hartberg | ||
| FT | Rapid Vienne | 3-1 (1-1) | Mattersburg | ||
| FT | SKN St. Poelten | 0-4 (0-1) | Wolfsberger AC | ||
| FT | Sturm Graz | 1-1 (0-0) | Austria Wien | ||
| FT | WSG Tirol | 1-1 (0-0) | Admira Wacker |
| FT | Slovacko | 2-0 (1-0) | Slavia Prague | ||
| FT | Bohemians 1905 | 0-0 (0-0) | Karvina |
| FT | FC Tambov | 0-0 (0-0) | Rubin Kazan | ||
| FT | FC Krasnodar | 2-0 (0-0) | FC Ufa | ||
| FT | PFC Sochi | 1-2 (0-1) | Arsenal Tula |
| FT | ND Triglav | 1-1 (1-1) | Mura | ||
| FT | Domzale | 1-1 (0-1) | NK Celje |
| FT | St. Johnstone | 0-1 (0-0) | Celtic |
| FT | AS Jeunesse Esch | 0-1 (0-0) | F91 Dudelange | ||
| FT | FC Muhlenbach Blue Boys | 0-3 (0-3) | FC Rodange 91 |
| FT | Varzim | 2-1 (1-0) | Mafra | ||
| FT | Sporting Covilha | 0-2 (0-0) | Chaves | ||
| FT | Casa Pia AC | 1-1 (0-1) | Cova da Piedade | ||
| FT | Estoril | 2-0 (1-0) | AVS Futebol SAD | ||
| FT | FC Porto B | 1-2 (1-1) | Oliveirense |
| FT | Zorya | 1-0 (0-0) | Olimpik Donetsk | ||
| FT | Vorskla | 1-0 (1-0) | Shakhtar Donetsk |
| FT | Union Berlin | 2-2 (1-0) | VFL Wolfsburg | ||
| FT | RB Leipzig | 1-1 (1-1) | Bayer Leverkusen |
| FT | FK Pohronie | 0-0 (0-0) | FK Senica | ||
| FT | Nitra | 0-1 (0-0) | Slovan Bratislava | ||
| FT | Ruzomberok | 1-1 (0-0) | Zemplin Michalovce | ||
| FT | Spartak Trnava | 2-1 (0-0) | Zlate Moravce | ||
| FT | Trencin | 2-1 (1-1) | SKF Sered | ||
| FT | Zilina | 2-2 (0-2) | DAC 1904 Dunajska Streda |
| FT | Everton | 1-1 (1-1) | Manchester United | ||
| FT | Tottenham Hotspur | 2-3 (2-1) | Wolverhampton Wanderers |
| FT | Celik Zenica | 1-1 (0-1) | Radnik Bijeljina |
| FT | Zira | 1-2 (1-0) | FK Qabala | ||
| FT | FK Neftchi | 1-1 (0-0) | Sabail |
| FT | Arminia Bielefeld | 1-0 (0-0) | Wehen Wiesbaden | ||
| FT | St. Pauli | 3-1 (2-0) | Osnabrueck | ||
| FT | VFL Bochum | 4-4 (2-2) | Sandhausen |
| FT | Levski Sofia | 1-2 (1-1) | Slavia Sofia |
| FT | Western United FC | 6-2 (4-2) | Central Coast Mariners | ||
| FT | Melbourne City FC | 1-0 (0-0) | Brisbane Roar FC |
