| FT | Botafogo RJ | 0-1 (0-1) | Atletico MG | ||
| FT | Corinthians | 2-0 (1-0) | Montevideo Wanderers | ||
| FT | Independiente | 1-0 (0-0) | Universidad Catolica |
| FT | Nacional | 0-1 (0-0) | Internacional | ||
| FT | San Lorenzo | 0-0 (0-0) | Cerro Porteno | ||
| FT | Athletico Paranaense | 0-1 (0-0) | Boca Juniors | ||
| FT | Emelec | 2-0 (1-0) | Flamengo | ||
| FT | Gremio | 2-0 (0-0) | Libertad |
| FT | America de Cali | 1-1 (0-1) | Patriotas |
| FT | Pyunik | 2-1 (2-0) | Jablonec | ||
| FT | Ventspils | 4-0 (1-0) | Gzira United | ||
| FT | FK Qabala | 0-2 (0-1) | Dinamo Tbilisi | ||
| FT | AEK Larnaca | 3-0 (0-0) | Levski Sofia | ||
| FT | Partizani | 0-1 (0-1) | FC Sheriff | ||
| FT | FC Utrecht | 1-1 (0-1) | Zrinjski Mostar | ||
| FT | Chikhura | 1-1 (1-0) | Aberdeen | ||
| FT | Budapest Honved | 0-0 (0-0) | Universitatea Craiova | ||
| FT | Alashkert FC | 0-3 (0-0) | FCSB | ||
| FT | Arsenal Tula | 0-1 (0-1) | FK Neftchi | ||
| FT | FK Haugesund | 2-0 (0-0) | Sturm Graz | ||
| FT | Flora Tallinn | 1-2 (1-1) | Eintracht Frankfurt | ||
| FT | Lechia Gdansk | 2-1 (1-0) | Broendby IF | ||
| FT | Mlada Boleslav | 1-1 (1-1) | Ordabasy Shymkent | ||
| FT | Molde | 0-0 (0-0) | Cukaricki | ||
| FT | Shakhtyor Soligorsk | 2-0 (1-0) | Esbjerg fB | ||
| FT | Yeni Malatyaspor | 2-2 (1-1) | Olimpija Ljubljana | ||
| FT | Connah's Quay Nomads | 0-1 (0-0) | Partizan Beograd | ||
| FT | Hapoel Beer Sheva | 2-0 (1-0) | Kairat Almaty | ||
| FT | Lokomotiv Plovdiv | 2-0 (1-0) | Spartak Trnava | ||
| FT | PFK CSKA Sofia | 1-0 (0-0) | Osijek | ||
| FT | IFK Norrkoeping | 2-0 (1-0) | FK Liepaja | ||
| FT | Piast Gliwice | 3-2 (0-1) | Riga FC | ||
| FT | Videoton FC Fehervar | 1-0 (1-0) | FC Vaduz | ||
| FT | FC Lucerne | 1-0 (0-0) | Klaksvik | ||
| FT | AS Jeunesse Esch | 0-1 (0-0) | Vitoria de Guimaraes | ||
| FT | AZ Alkmaar | 0-0 (0-0) | Haecken | ||
| FT | Aris Thessaloniki FC | 0-0 (0-0) | AEL Limassol | ||
| FT | DAC 1904 Dunajska Streda | 1-2 (1-2) | Atromitos | ||
| FT | La Gantoise | 6-3 (5-1) | FCV Farul Constanta | ||
| FT | Buducnost Podgorica | 1-3 (0-2) | Zorya | ||
| FT | Domzale | 2-2 (1-1) | Malmoe FF | ||
| FT | Rangers | 2-0 (1-0) | FC Progres Niederkorn | ||
| FT | Strasbourg | 3-1 (1-1) | Maccabi Haifa | ||
| FT | Wolverhampton Wanderers | 2-0 (1-0) | Crusaders | ||
| FT | Espanyol | 4-0 (0-0) | Stjarnan | ||
| FT | Legia Warszawa | 1-0 (1-0) | KuPS | ||
| FT | Shamrock Rovers | 2-1 (1-1) | Apollon Limassol | ||
| FT | Torino | 3-0 (2-0) | Debreceni VSC | ||
| FT | Valur | 1-1 (1-0) | Ludogorets Razgrad |
| FT | DC United | 1-8 (1-1) | Marseille | ||
| FT | Sporting CP | 2-2 (1-2) | Liverpool | ||
| FT | Queretaro FC | 0-2 (0-0) | Real Betis | ||
| FT | Santa Clara | 2-0 (1-0) | Sporting Ideal | ||
| FT | Gaziantep FK | 0-4 (0-2) | Alanyaspor | ||
| FT | Altinordu | 2-2 (1-1) | Ankaragucu | ||
| FT | Hoffenheim | 0-0 (0-0) | Hellas Verona | ||
| FT | Lecce | 6-0 (3-0) | Virtus Bolzano | ||
| FT | Goztepe | 1-0 (0-0) | Menemen | ||
| FT | Fenerbahce | 1-2 (0-0) | Hertha Berlin | ||
| FT | Asteras Tripolis | 0-0 (0-0) | Konyaspor | ||
| FT | Augsburg | 4-1 (2-0) | Galatasaray | ||
| FT | Braga | 2-2 (1-0) | Tondela | ||
| FT | Feirense | 1-0 (1-0) | Aves | ||
| FT | Fuenlabrada | 1-0 (0-0) | Deportivo Alaves | ||
| FT | Levante | 2-0 (1-0) | Almeria | ||
| FT | Hoffenheim | 3-3 (2-2) | Trabzonspor | ||
| FT | FC Emmen | 3-0 (2-0) | OFI Crete | ||
| FT | Derby County | 0-2 (0-1) | Girona |
| Pen. | Houston Dynamo FC | 1-1(1-1) | CF America* | ||
| FT | Real Salt Lake | 0-1 (0-0) | Tigres |
