| FT | Minnesota United | 2-1 (1-1) | Houston Dynamo FC | ||
| FT | LA Galaxy | 2-3 (0-1) | New York Red Bulls | ||
| FT | Colorado Rapids | 1-2 (1-0) | Orlando City | ||
| FT | New York City FC | 3-1 (2-1) | FC Dallas | ||
| FT | Los Angeles FC | 1-0 (0-0) | Seattle Sounders FC |
| FT | Independiente Medellin | 1-0 (0-0) | Deportivo Pasto | ||
| FT | Leones | 1-1 (0-1) | Patriotas | ||
| FT | Tolima | 0-0 (0-0) | Santa Fe | ||
| FT | Junior FC | 0-0 (0-0) | Alianza FC | ||
| FT | Once Caldas | 2-2 (1-1) | America de Cali | ||
| FT | La Equidad | 1-0 (0-0) | Atletico Nacional |
| FT | Tigres | 2-2 (1-1) | Monterrey | ||
| FT | Pachuca | 0-0 (0-0) | Atlas | ||
| FT | CF America | 1-0 (0-0) | Santos Laguna | ||
| FT | CD Guadalajara | 0-2 (0-1) | Leon | ||
| FT | Club Universidad Nacional | 1-1 (1-0) | Queretaro FC | ||
| FT | Veracruz | 1-2 (0-1) | Cruz Azul |
| FT | Palestino | 2-3 (1-0) | O'Higgins | ||
| FT | Deportes Temuco | 0-2 (0-0) | Union La Calera | ||
| FT | Universidad de Chile | 1-2 (0-0) | Universidad de Concepcion | ||
| FT | San Luis | 1-1 (0-0) | Universidad Catolica |
| FT | Olimpia | 3-0 (2-0) | Luqueno | ||
| FT | Libertad | 1-1 (0-0) | Deportivo Santani |
| FT | Atletico MG | 1-0 (0-0) | Corinthians | ||
| FT | Bahia | 0-0 (0-0) | Athletico Paranaense | ||
| FT | Ceara | 0-3 (0-1) | Flamengo | ||
| FT | Fluminense | 1-1 (0-1) | Sao Paulo | ||
| FT | Palmeiras | 0-0 (0-0) | Chapecoense AF | ||
| FT | Parana Clube | 1-2 (0-1) | Sport Recife | ||
| FT | Internacional | 0-0 (0-0) | Cruzeiro |
| FT | LDU de Quito | 2-1 (1-0) | Barcelona SC | ||
| FT | Tecnico Universitario | 2-2 (1-0) | El Nacional |
| FT | Boavista | 1-0 (0-0) | Pacos de Ferreira | ||
| FT | Rio Ave | 2-1 (0-0) | Chaves | ||
| FT | Maritimo | 0-1 (0-0) | FC Porto | ||
| FT | Cova da Piedade SAD | 0-1 (0-0) | Braga |
| FT | Rennes | 2-1 (1-1) | Toulouse | ||
| FT | Angers | 1-1 (0-1) | Marseille | ||
| FT | Paris St-Germain | 2-2 (0-1) | Guingamp |
| FT | Crotone | 4-1 (3-1) | Sassuolo | ||
| FT | Atalanta | 3-1 (2-0) | Genoa | ||
| FT | Benevento | 3-3 (1-1) | Udinese | ||
| FT | Bologna | 1-2 (0-2) | AC Milan | ||
| FT | Hellas Verona | 1-3 (1-1) | SPAL | ||
| FT | Sampdoria | 4-1 (3-0) | Cagliari | ||
| FT | Fiorentina | 3-0 (1-0) | Naples | ||
| FT | Torino | 0-1 (0-0) | Lazio |
| FT | Getafe | 1-1 (1-1) | Girona | ||
| FT | Deportivo Alaves | 0-1 (0-0) | Atletico Madrid | ||
| FT | Valencia | 0-0 (0-0) | Eibar | ||
| FT | Deportivo La Coruna | 2-4 (1-2) | Barcelona |
| FT | Anderlecht | 3-1 (1-0) | Sporting Charleroi | ||
| FT | La Gantoise | 1-3 (1-0) | Standard Liege |
| FT | Patronato de Parana | 0-0 (0-0) | San Lorenzo | ||
| FT | Belgrano | 1-0 (1-0) | Colon |
| FT | Hapoel Haifa | 2-2 (0-0) | Maccabi Tel Aviv |
| FT | Molde | 0-1 (0-1) | Odds Ballklubb | ||
| FT | Sandefjord | 0-1 (0-0) | Brann | ||
| FT | Sarpsborg 08 | 0-0 (0-0) | Bodoe/Glimt | ||
| FT | Start | 0-1 (0-0) | FK Haugesund | ||
| FT | Tromsoe | 0-0 (0-0) | Kristiansund BK | ||
| FT | Stroemsgodset | 0-1 (0-1) | Rosenborg |
| FT | Numancia | 3-0 (2-0) | Real Oviedo | ||
| FT | Sporting Gijon | 2-1 (1-1) | Albacete | ||
| FT | Cultural Leonesa | 2-1 (1-0) | Cordoba | ||
| FT | Rayo Vallecano | 3-1 (1-1) | Tenerife | ||
| FT | Lorca FC | 1-0 (0-0) | Gimnastic |
| FT | FCSB | 1-1 (0-0) | CFR 1907 Cluj |
| FT | Beroe | 0-4 (0-2) | Levski Sofia | ||
| FT | Botev Plovdiv | 2-1 (1-0) | PFK CSKA Sofia |
| FT | FK Zemun | 0-0 (0-0) | Mladost Lucani | ||
| FT | Javor | 3-0 (3-0) | Borac Cacak | ||
| FT | Macva Sabac | 2-1 (0-1) | FK Radnik Surdulica | ||
| FT | Rad Beograd | 2-0 (2-0) | Backa Backa Palanka |
| FT | Napredak | 0-2 (0-0) | FK Crvena Zvezda | ||
| FT | Vojvodina | 2-1 (1-1) | Partizan Beograd | ||
| FT | Cukaricki | 3-0 (0-0) | FK Spartak Subotica | ||
| FT | Radnicki Nis | 3-0 (3-0) | Vozdovac |
| FT | FAR Rabat | 1-2 (1-0) | Chabab Atlas Khenifra | ||
| FT | Ittihad Tanger | 0-0 (0-0) | Wydad Casablanca | ||
| FT | Racing de Casablanca | 1-3 (0-2) | RSB Berkane | ||
| FT | Hassania Agadir | 1-0 (1-0) | Rapide Club Oued Zem |
| FT | Rudes | 3-2 (1-1) | Cibalia | ||
| FT | Slaven | 0-0 (0-0) | Hajduk Split |
| FT | Olimpija Ljubljana | 0-0 (0-0) | Gorica | ||
| FT | NK Krsko | 1-2 (1-2) | Aluminij |
| FT | Sturm Graz | 4-2 (2-1) | Rapid Vienne | ||
| FT | SKN St. Poelten | 0-2 (0-1) | Red Bull Salzbourg |
| FT | FC Ashdod | 1-0 (0-0) | Hapoel Ashkelon |
| FT | Zorya | 1-0 (0-0) | FC Lviv | ||
| FT | Vorskla | 0-1 (0-0) | Dynamo Kyiv |
| FT | Smolevichy | 1-1 (0-0) | FK Vitebsk | ||
| FT | FK Gorodeya | 1-1 (1-0) | Torpedo Zhodino |
| FT | Slavia Prague | 0-0 (0-0) | Slovacko | ||
| FT | FC Zlin | 1-1 (1-0) | Bohemians 1905 | ||
| FT | Teplice | 1-2 (1-1) | Sigma Olomouc | ||
| FT | Jablonec | 2-0 (1-0) | Slovan Liberec |
| FT | Yeni Malatyaspor | 0-0 (0-0) | Akhisarspor | ||
| FT | Ankaraspor | 1-4 (1-0) | Istanbul Basaksehir | ||
| FT | Galatasaray | 2-0 (1-0) | Besiktas |
| FT | Jagiellonia Bialystok | 0-1 (0-0) | Wisla Krakow |
| FT | FC Midtjylland | 3-0 (2-0) | AaB | ||
| FT | Broendby IF | 3-1 (1-1) | FC Nordsjaelland |
| FT | AEK Larnaca | 2-0 (1-0) | Omonia Nicosia | ||
| FT | APOEL Nicosia | 2-1 (1-1) | Apollon Limassol |
| FT | AOK Kerkyra | 0-0 (0-0) | AEK Athens | ||
| FT | Asteras Tripolis | 2-1 (0-0) | Apollon Smirnis | ||
| FT | Lamia | 2-1 (1-0) | PAS Giannina | ||
| FT | Levadiakos | 0-1 (0-0) | Atromitos | ||
| FT | Olympiacos | 4-0 (3-0) | Panetolikos | ||
| FT | Panathinaikos | 0-3 (0-1) | PAOK Thessaloniki FC | ||
| FT | Platanias | 1-2 (0-0) | Panionios | ||
| FT | Xanthi | 1-0 (0-0) | AE Larissa |
| FT | Mainz 05 | 3-0 (1-0) | RB Leipzig | ||
| FT | Werder Bremen | 1-1 (1-1) | Borussia Dortmund |
| FT | Amkar-Perm | 0-2 (0-1) | Spartak Moscow | ||
| FT | Zenit St. Petersburg | 0-0 (0-0) | CSKA Moscow | ||
| FT | FC Rostov | 2-0 (0-0) | Tosno |
| FT | Djurgaarden | 1-2 (0-1) | Hammarby | ||
| FT | GIF Sundsvall | 2-1 (1-0) | Elfsborg | ||
| FT | IFK Norrkoeping | 1-2 (0-0) | Trelleborgs FF | ||
| FT | Kalmar FF | 3-0 (3-0) | Malmoe FF |
| FT | Lyon (F) | 1-0 (1-0) | Manchester City (F) | ||
| FT | VFL Wolfsburg (F) | 2-0 (0-0) | Chelsea (F) |
| FT | West Ham United | 1-4 (1-2) | Manchester City | ||
| FT | Manchester United | 2-1 (1-0) | Arsenal |
| FT | FK Sarajevo | 3-1 (2-0) | Radnik Bijeljina |
| FT | Nea Salamis | 3-1 (0-0) | Olympiakos Nicosia |
| FT | FK Kauno Zalgiris | 2-3 (1-1) | Atlantas Klaipeda | ||
| FT | Stumbras Kaunas | 0-2 (0-1) | Riteriai |
| FT | Ilves | 1-1 (1-0) | SJK | ||
| FT | KuPS | 1-1 (0-1) | FC Lahti | ||
| FT | VPS | 1-2 (1-0) | HJK | ||
| FT | Kemi City FC | 2-3 (1-1) | IFK Mariehamn |
| FT | Sumqayit | 1-2 (0-2) | Sabail |
| FT | Oliveirense | 1-2 (0-2) | Santa Clara | ||
| FT | Academico Viseu | 1-0 (0-0) | Gil Vicente | ||
| FT | Arouca | 1-4 (0-2) | Penafiel | ||
| FT | Benfica B | 0-1 (0-0) | Vitoria de Guimaraes B | ||
| FT | FC Porto B | 0-4 (0-2) | Braga B | ||
| FT | Famalicao | 1-2 (1-1) | Uniao da Madeira | ||
| FT | Real SC | 2-3 (1-0) | Cova da Piedade | ||
| FT | Sporting Covilha | 0-1 (0-1) | Academica | ||
| FT | Varzim | 2-0 (1-0) | Sporting CP B |
| FT | GOSK Gabela | 1-0 (0-0) | Celik Zenica |
| FT | Gaz Metan Medias | 2-1 (1-0) | Botosani |
| FT | FC Bâle | 6-1 (2-1) | Thun | ||
| FT | Lugano | 2-1 (1-0) | Saint-Gall | ||
| FT | FC Zürich | 3-3 (0-1) | Sion |
| FT | Drita | 3-1 (0-0) | Feronikeli | ||
| FT | FC Prishtina | 3-2 (0-0) | Llapi | ||
| FT | KF Vellaznimi | 0-0 (0-0) | Besa Peje | ||
| FT | Trepca 89 | 0-0 (0-0) | KF Flamurtari |
| FT | Roeselare | 1-0 (1-0) | Union St.Gilloise | ||
| FT | Westerlo | 1-1 (0-0) | Tubize |
| FT | CS Fola Esch | 1-1 (0-1) | AS Jeunesse Esch | ||
| FT | US Hostert | 1-3 (0-2) | FC Victoria Rosport | ||
| FT | Una Strassen | 2-1 (0-1) | US Mondorf les Bains | ||
| FT | Union Esch FC | 0-3 (0-3) | FC Differdange 03 | ||
| FT | Union Titus Petange | 1-3 (1-1) | F91 Dudelange |
| FT | Cracovia | 4-2 (1-2) | Termalica Nieciecza |
| FT | SP Libertas | 3-0 (0-0) | Domagnano | ||
| Pen. | Tre Penne Galazzano | 2-2(2-2) | Tre Fiori* |
| FT | Beerschot | 0-0 (0-0) | Royal Antwerp |
| FT | ADO La Haye | 3-3 (2-1) | PSV Eindhoven | ||
| FT | Ajax Amsterdam | 3-0 (1-0) | AZ Alkmaar | ||
| FT | FC Groningen | 4-0 (2-0) | Excelsior | ||
| FT | Feyenoord | 3-1 (1-1) | Sparta Rotterdam | ||
| FT | Heracles | 2-2 (2-0) | FC Utrecht | ||
| FT | NAC Breda | 3-0 (2-0) | SC Heerenveen | ||
| FT | PEC Zwolle | 0-1 (0-0) | Willem II | ||
| FT | VVV-Venlo | 1-4 (1-1) | Roda JC Kerkrade | ||
| FT | Vitesse Arnhem | 5-0 (1-0) | FC Twente |
| FT | Lyngby | 1-3 (0-1) | Randers FC | ||
| FT | Soenderjyske Fodbold | 2-0 (0-0) | OB |
| FT | Ventspils | 1-0 (1-0) | Riga FC |
| FT | Tulevik Viljandi | 2-1 (1-0) | Parnu JK Vaprus |
| FT | Changchun Yatai | 2-1 (1-1) | Shanghai Port | ||
| FT | Beijing Guoan | 4-3 (3-1) | Guizhou F.C. | ||
| FT | Chongqing Liangjiang Athletic | 0-1 (0-1) | Guangzhou City | ||
| FT | Shandong Taishan | 2-1 (0-1) | Henan FC | ||
| FT | Shanghai Shenhua | 1-0 (0-0) | Dalian Professional FC |
| FT | Dingnan United | 1-2 (1-2) | Guangdong Huanan | ||
| FT | Qingdao FC | 1-1 (0-0) | Wuhan Yangtze River | ||
| FT | Shanghai Shenxin | 2-1 (1-0) | Nei Mongol Zhongyou FC | ||
| FT | Xinjiang Tianshan | 2-2 (1-1) | Dalian Transcendence | ||
| FT | Shenzhen FC | 4-1 (1-1) | Cangzhou Mighty Lions F.C. |
| FT | FC Heidenheim | 2-0 (2-0) | Sandhausen | ||
| FT | Ingolstadt | 1-5 (1-1) | Holstein Kiel | ||
| FT | MSV Duisburg | 4-1 (0-0) | Jahn Regensburg |
| FT | Celtic | 5-0 (3-0) | Rangers |
| FT | Suwon FC | 1-2 (0-0) | Daejeon Hana Citizen | ||
| FT | Chungnam Asan FC | 1-2 (1-2) | Gwangju FC | ||
| FT | Seoul E-Land FC | 2-1 (0-1) | Ansan Greeners |
| FT | Gamba Osaka | 3-0 (0-0) | Sagan Tosu |
| FT | Jeonbuk Hyundai Motors FC | 2-0 (1-0) | Suwon Samsung Bluewings | ||
| FT | Gangwon FC | 0-0 (0-0) | Pohang Steelers | ||
| FT | Incheon United | 2-3 (2-1) | Gyeongnam FC |
| FT | Antigua and Barbuda | 0-2 (0-0) | Jamaïque |
