| 59' | Torreense | 2-1 (1-1) | Uniao de Leiria |
| 71' | Lille | 1-2 (1-2) | Lyon |
| 88' | Inter Milan | 2-2 (1-1) | Naples |
| Abd. | Kayserispor | 3-2 | Artis Brno |
| 02h00 | Atletico de San Luis | Tigres |
| FT | Leon | 2-1 (1-0) | Cruz Azul | ||
| FT | Santos Laguna | 1-3 (1-2) | Necaxa | ||
| FT | Monterrey | 0-1 (0-0) | Toluca | ||
| FT | Club Universidad Nacional | 1-1 (0-0) | Queretaro FC |
| FT | Sochaux | 0-3 (0-1) | Lens | ||
| FT | Chantilly US | 1-3 (1-0) | Rennes | ||
| Pen. | *Le Mans | 0-0(0-0) | Nancy | ||
| FT | Metz | 0-4 (0-2) | Montpellier | ||
| Pen. | Nantes | 1-1(1-1) | Nice* |
| FT | Lecce | 1-2 (1-0) | Parma Calcio 1913 | ||
| FT | Fiorentina | 1-1 (0-0) | AC Milan | ||
| FT | Hellas Verona | 0-1 (0-0) | Lazio |
| FT | Barcelona | 3-2 (2-2) | Real Madrid |
| FT | Levadiakos | 3-1 (2-0) | NFC Volos | ||
| FT | OFI Crete | 4-0 (2-0) | Asteras Tripolis | ||
| FT | Aris Thessaloniki FC | 1-1 (1-1) | AEK Athens | ||
| FT | Panathinaikos | 3-0 (3-0) | Panserraikos FC |
| FT | Portimonense | 0-0 (0-0) | Felgueiras 1932 | ||
| FT | Chaves | 2-3 (2-1) | Maritimo | ||
| FT | FC Porto B | 2-1 (0-1) | Sporting CP B | ||
| FT | Oliveirense | 3-4 (2-1) | Feirense |
| FT | Nacional | 3-3 (2-2) | Santa Clara | ||
| FT | Moreirense | 1-0 (0-0) | Tondela |
| FT | FC Ashdod | 2-5 (0-2) | Hapoel Ironi Kiryat Shmona |
| FT | Derby County | 1-3 (1-0) | Leeds United | ||
| FT | Portsmouth | 1-4 (1-2) | Arsenal | ||
| Pen. | *Hull City | 0-0(0-0) | Blackburn Rovers | ||
| FT | Norwich City | 5-1 (2-0) | Walsall | ||
| FT | Sheffield United | 3-4 (1-2) | Mansfield Town | ||
| Pen. | Swansea City | 2-2(1-1) | West Bromwich Albion* | ||
| AP | West Ham United | AP 2-1 | Queens Park Rangers | ||
| FT | Manchester United | 1-2 (0-1) | Brighton & Hove Albion |
| FT | Borussia Moenchengladbach | 4-0 (3-0) | Augsburg | ||
| FT | Bayern Munich | 8-1 (2-1) | VFL Wolfsburg |
| FT | Dundee FC | 0-1 (0-1) | Hearts | ||
| FT | Aberdeen | 0-2 (0-1) | Rangers |
| FT | Mantova | 1-1 (0-1) | Palermo | ||
| FT | Calcio Padova | 2-0 (1-0) | Modena |
| FT | SC Heerenveen | 2-2 (1-2) | Feyenoord | ||
| FT | Go Ahead Eagles | 2-2 (1-1) | Fortuna Sittard | ||
| FT | Telstar | 2-3 (0-2) | Ajax Amsterdam | ||
| FT | Sparta Rotterdam | 2-0 (1-0) | Heracles |
| FT | Marsaxlokk FC | 2-1 (1-1) | Birkirkara |
| FT | Leganes | 3-0 (2-0) | Real Valladolid | ||
| FT | Granada CF | 0-0 (0-0) | Castellon | ||
| FT | Malaga | 2-1 (2-1) | AD Ceuta FC |
| FT | Rayo Vallecano | 2-1 (2-1) | Mallorca | ||
| FT | Levante | 1-1 (0-0) | Espanyol |
| FT | Anorthosis | 1-0 (1-0) | Ethnikos Achnas | ||
| FT | Enosis Paralimni | 0-1 (0-1) | Apollon Limassol |
| FT | Gzira United | 0-2 (0-2) | Zabbar St. Patrick | ||
| FT | Hibernians | 0-2 (0-0) | Mosta | ||
| FT | Naxxar Lions FC | 1-0 (0-0) | Tarxien Rainbows |
| FT | Wellington Phoenix | 2-2 (0-2) | Adelaide United | ||
| FT | Melbourne City FC | 0-1 (0-0) | Newcastle Jets |
