| 03h00 | CD Guadalajara | Leon | |||
| 04h00 | Mazatlan FC | Necaxa | |||
| 05h00 | Monterrey | FC Juarez |
| 01h30 | Atlanta United | Inter Miami CF | |||
| 01h30 | New England Revolution | CF Montreal | |||
| 01h30 | New York City FC | Philadelphia Union | |||
| 01h30 | Toronto FC | Columbus Crew | |||
| 02h15 | Orlando City | Charlotte FC | |||
| 02h30 | Houston Dynamo FC | Vancouver Whitecaps | |||
| 02h30 | Minnesota United | FC Cincinnati | |||
| 02h30 | Nashville SC | Chicago Fire FC | |||
| 02h30 | Sporting Kansas City | Colorado Rapids | |||
| 03h30 | Real Salt Lake | FC Dallas | |||
| 04h30 | Los Angeles FC | Austin FC | |||
| 04h30 | Portland Timbers | LA Galaxy | |||
| 04h30 | Seattle Sounders FC | San Jose Earthquakes |
| 00h00 | Fluminense | Atletico MG | |||
| 02h30 | Botafogo RJ | Sao Paulo |
| 02h30 | Lanus | Independiente Medellin |
| 02h10 | Central Cordoba de Santiago | Temperley |
| 18h45 | Bologna | Shakhtar Donetsk | |||
| 18h45 | Sparta Prague | ?-? | Red Bull Salzbourg | ||
| 21h00 | Celtic | Slovan Bratislava | |||
| 21h00 | Club Brugge | Borussia Dortmund | |||
| 21h00 | Manchester City | Inter Milan | |||
| 21h00 | Paris St-Germain | Girona |
| 20h45 | Brighton & Hove Albion | Wolverhampton Wanderers | |||
| 21h00 | Coventry City | Tottenham Hotspur |
| 14h30 | Roma (F) | Servette | |||
| 14h30 | WFC Osijek | FC Twente (F) | |||
| 18h45 | Paris FC (F) | Manchester City (F) | |||
| 19h00 | BK Häcken FF (F) | Arsenal Women | |||
| 19h00 | Hammarby IF | Benfica (F) | |||
| 19h00 | Juventus | Paris St-Germain (F) | |||
| 19h30 | Anderlecht | Vaalerenga | |||
| 20h00 | Fiorentina | VFL Wolfsburg (F) |
| 20h00 | Ajax Amsterdam | Fortuna Sittard |
| 19h30 | Lausanne | Lugano |
| 19h00 | Samsunspor | Istanbul Basaksehir |
| 19h00 | Real Betis | Getafe |
| 19h00 | Torpedo Kutaisi | Iberia 1999 |
| 18h00 | Kristiansund BK | Molde | |||
| 19h00 | Brann | KFUM |
| 19h00 | GAIS | Malmoe FF |
| 18h00 | Enosis Paralimni | APOEL Nicosia | |||
| 18h00 | Pafos FC | Nea Salamis |
| 18h00 | FK IMT Beograd | FK Radnicki 1923 |
| 16h30 | Nomme JK Kalju | Nomme United | |||
| 18h00 | Parnu JK Vaprus | Tammeka |
| 17h00 | Dynamo Kyiv | Vorskla |
| 17h00 | NK Celje | Maribor |
| 16h30 | Maccabi Tel Aviv | Hapoel Jerusalem FC |
| 16h30 | Slavia Sofia | Ludogorets Razgrad |
| 12h00 | Ulsan HD FC | Kawasaki Frontale | |||
| 14h00 | Shanghai Port | Johor Darul Ta'zim |
| 12h00 | Nagoya Grampus | Albirex Niigata |
| FT | Atletico de San Luis | 3-1 (2-1) | Cruz Azul | ||
| FT | CF America | 3-0 (1-0) | Atlas | ||
| FT | Pachuca | 2-2 (0-1) | Toluca | ||
| FT | Queretaro FC | 1-0 (1-0) | Tigres | ||
| FT | Club Universidad Nacional | 1-0 (0-0) | Puebla |
| FT | Colo Colo | 1-1 (0-1) | River Plate |
| FT | Fortaleza | 0-2 (0-1) | Corinthians |
| FT | 2 de Mayo | 0-2 (0-1) | General Caballero JLM |
